Oleanolic Acid Powder

Plant Source: Olive Leaf
CAS No: 508-02-1
Specification: 60%-98% oleanolic acid
Appearance: White powder
Test Method: Titration
Lead time: 1-3 days
Storage: Cool dry place and avoid light
Shelf Life: 2 years
MOQ: 1KG
Sample: Free sample available
Certifications: GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

Product Details


China Manufacturers Best Suppliers supply Oleanolic Acid powder for sale.

Xi'an Kintaihealth® is a premier manufacturer of top - notch Oleanolic acid powder. Leveraging cutting - edge extraction and purification technologies, we offer pharmaceutical - grade products with a purity that constantly surpasses 98%. As a vital naturally - occurring pentacyclic triterpenoid (CAS: 508 - 02 - 1), Oleanolic acid is in its core bioactive form, ensuring high bioavailability for various uses.Our GMP - compliant production process guarantees outstanding stability and dependability. Oleanolic acid powder is widely used. If you want to buy Oleanolic acid powder, please contact us directly!

 

  What is Oleanolic Acid Powder?  

Oleanolic acid Powder(OA) is a pentacyclic triterpenoid widely found in various plants, especially in olive peel. Because it has a variety of biological activities, including anti-inflammatory, anti-diabetic, anti-cancer, antioxidant, heart protection, liver protection, antibacterial and anti-parasitic activities, it can be used in the clinical treatment of hepatitis, is a highly valuable product.

Oleanolic Acid Powder

Product Details

Chemical & Physical Properties

CAS Number 508-02-1 Density 1.0261 (rough estimate)
Molecular Formula C30H48O3 Molecular Weight 456.7
Melting Point >300 ℃ (lit.) Boiling Point 502.79 ℃ (rough estimate)
Solubleness Soluble in chloroform (very slight), DMSO (slight, heated), methanol (slight, heated) Test Mehod Titration

Structure of Oleanolic Acid

  Kintai Oleanolic Acid Powder Advantages  

 

High Potency & Clinically Proven Efficacy : Our Oleanolic Acid powder is available in Pharmaceutical Grade (≥98% purity) and Nutraceutical Grade (≥95% purity), rigorously analyzed by HPLC to ensure exceptional hepatoprotective, anti - inflammatory, and antioxidant properties. Each batch ensures uniform bioactivity, facilitating the development of premium products.

Multi - Industry Application :

• Nutraceuticals : Liver function enhancer, supports metabolic health, and aids in cholesterol management for dietary supplements.

• Cosmetics : Improves skin firmness, mitigates oxidative damage, and promotes a radiant complexion as a key ingredient in skincare products.

• Pharmaceuticals : Prospective uses in research for anti - viral, anti - diabetic, and liver disorder - related therapies.

Strict Quality Control : Produced in a GMP - compliant plant, our Oleanolic Acid powder provides full traceability, along with detailed COA, MSDS, and thorough examinations for heavy metals, residual solvents, and microbial impurities.

  Interested? We’d Love to Send You a Sample!  

  Oleanolic Acid Powder Production process  

 

Xi'an Kintaihealth® employs a rigorous, multi - stage production process to ensure the highest quality and purity of our Oleanolic Acid powder. Here’s an overview of our manufacturing workflow:

Unlocking the Potential of Oleanolic Acid: Integrating Pharmacological  Insights and Advancements in Delivery Systems

1. Raw Material Sourcing

• Botanical Selection: We source premium plant materials rich in Oleanolic Acid, such as Olea europaea (olive leaves), Ligustrum lucidum (glossy privet), or Gynostemma pentaphyllum (jiaogulan).

• Quality Verification: Each batch of raw material undergoes identity testing (e.g., HPLC, TLC) and contamination screening (heavy metals, pesticides, microbial limits) to meet GMP standards.

2. Extraction

• Solvent Extraction: Raw materials are crushed and subjected to ethanol or methanol extraction under controlled temperature and pressure to isolate triterpenoid compounds, including Oleanolic Acid.

• Concentration: The extract is filtered and concentrated via vacuum distillation to remove solvents, yielding a crude oleanolic acid - rich resin.

3. Purification

• Chromatographic Separation: The crude resin undergoes column chromatography using silica gel or macroporous resins to isolate and purify Oleanolic Acid from other triterpenoids (e.g., ursolic acid).

• Recrystallization: The purified fraction is dissolved in ethanol or acetone and recrystallized to achieve pharmaceutical - grade purity (≥98%).

4. Refinement & Drying

• Activated Carbon Treatment: The recrystallized product is treated with activated carbon to remove color impurities and residual solvents.

• Spray Drying: The refined solution is spray - dried under sterile conditions to produce a fine, free - flowing powder with optimal particle size for bioavailability.

This meticulous process guarantees that Kintai’s Oleanolic Acid powder meets the highest pharmaceutical, nutraceutical, and cosmetic industry standards, delivering consistent efficacy and safety for diverse applications.

  Oleanolic Acid Powder COA  

Oleanolic acid powderCOA 

  Interested? We’d Love to Send You a Sample!  

  Oleanolic acid Powder Benefits  

 

1. Hepatoprotective effect : Oleanolic acid powder can alleviate liver injury, promote liver cell regeneration, accelerate the recovery of necrotic tissue, inhibit liver fiber hyperplasia and prevent liver cirrhosis.

2. Antibacterial action : OA has antibacterial properties and is a broad-spectrum antibacterial drug, which can be used to treat bronchitis, periodontitis, acute tonsillitis, urinary system infection, etc.

3. Antioxidant : Oleanolic acid can remove free radicals in the body, inhibit the generation of lipid peroxides, improve the stability of the body lipid, and have a protective effect on the body.

4. Other effects : Oleanolic acid also has anti-inflammatory, hypoglycemic and lipid lowering, correcting protein metabolism disorders and other effects.

Benefits of Oleanolic acid

 

  Oleanolic Acid Powder Applications  


Oleanolic acid can be used as an anti-hepatitis drug in the treatment of chronic hepatitis, acute jaundice hepatitis and other liver diseases, as well as bronchitis, dysentery, acute gastroenteritis and other infectious diseases.

Hepatitis medications: Video, Causes, & Meaning | Osmosis

  Oleanolic Acid Powder Dosage  

Application Field

Target Population & Indication

Professional Dosage Recommendation

Precautions

Healthcare
(Adjunctive Liver Disease Therapy)

Adults with chronic hepatitis or hepatic dysfunction for adjuvant treatment

Oral: 30 mg (3 tablets of 10 mg each) TID, or as per medical prescription

Under physician supervision; regular liver function monitoring is required. Contraindicated for pregnant/lactating women and children due to insufficient safety data.

Dietary Supplements
(Metabolic & Immune Support)

Adults for metabolic regulation and immune enhancement

50–100 mg daily, divided into 1–2 administrations

Avoid prolonged high-dose use; consult a healthcare provider before co-administration with other drugs to mitigate potential interactions.

Cosmetics
(Topical Dermatological Use)

All skin types for improving dermal elasticity and anti-aging

Formulated at 0.1%–2% concentration in skincare products; adhere to product-specific instructions

Perform patch testing prior to initial use; avoid ocular contact. Exercise caution in cases of cutaneous lesions or allergic predisposition.

 

  Safety of KINTAIS Oleanolic Acid Powder  

 

1. Allergic Reactions and Sensitivities

Oleanolic acid powder is generally well - tolerated by most individuals. However, as a naturally - derived triterpenoid compound, those with known allergies to plants from which it is extracted, such as olive leaves, glossy privet, or jiaogulan, may be susceptible to adverse reactions. It is highly recommended to conduct an initial sensitivity test, particularly when incorporating oleanolic acid into new dietary supplements or formulations. In the event of symptoms like skin rashes, itching, swelling, or respiratory distress, discontinue use immediately and consult a medical professional.

2. Safety and Toxicity Research

• General Safety Limits : Currently, there is no universally standardized maximum intake limit for oleanolic acid. Nevertheless, clinical trials commonly employ doses ranging from 50 - 200 mg/day, with no significant adverse effects reported. Doses exceeding 300 mg/day might elevate the risk of experiencing mild gastrointestinal symptoms, including abdominal bloating, nausea, or diarrhea.

• Toxicity Data : Animal studies (using rats) have indicated that the acute oral LD₅₀ of oleanolic acid exceeds 2,000 mg/kg, suggesting a relatively low acute toxicity profile. Long - term studies (lasting up to 12 months) at doses of 100 - 150 mg/day have shown no severe systemic toxicity concerns.

• Purity and Quality : Kintai's Oleanolic acid powder is manufactured using state - of - the - art extraction and purification techniques, attaining a pharmaceutical - grade purity of ≥98% (validated by HPLC). Stringent testing procedures are implemented to ensure that contaminants, such as heavy metals (e.g., lead, mercury) and residual solvents, are maintained at minimal levels, thereby meeting the most stringent quality benchmarks.

3. International Compliance

• EU Regulations : Oleanolic acid is deemed a safe ingredient for use in food supplements and nutraceutical products within the European Union, provided it complies with the stipulated purity and safety requirements.

• US FDA : The FDA has not formulated specific regulations regarding oleanolic acid as a dietary supplement ingredient. However, when utilized as a food additive or in pharmaceutical products, it must conform to relevant Good Manufacturing Practice (GMP) guidelines.

• Asia : In countries like China, Japan, and South Korea, oleanolic acid is approved for use in dietary supplements, functional foods, and cosmeceuticals, as long as it adheres to local purity and safety standards.

Medication Safety Tips to Know - Burt's Rx Pharmacy

Interested? We’d Love to Send You a Sample!

 

Why Choose Oleanolic Powder by Kintaihealth®?
1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce oleanolic acid powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.

KINTAI is a leading manufacturer and supplier of olive extract powder. With our state-of-the-art research and development center, production facilities, multiple patents, and quality certifications, we ensure the highest standards of product quality. We support customized products and provide integrated service solutions. Our fast delivery and secure packaging guarantee a great customer experience. We provide free samples for testing, if you want to purchase high quality Oleanolic Acid Powder, please feel free to contact us at herb@kintaibio.com.

About Us


factory equipment

  KINTAI Certifications  

Our Certifications

  Packaging and Delivery  

Production Process

Packing and shipping

Hot Tags: oleanolic acid powder, olive extract, OA, olive leaf extract powder, Suppliers, Manufacturers, Factory, Buy, price, for sale, producer, free sample.

Send