Caffeic Acid Powder
Specification: 98% Caffeic acid
Appearance: yellow powder
Test Method: HPLC
Lead time: 1-3 days
Storage: Cool dry place and avoid light
Shelf Life: 2 years
MOQ: 1KG
Sample: Free sample available
Certifications: GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL
Payment: Multiple terms acceptable like T/T, LC, DA
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Product Deatils
Xi'an Kintaihealth® operates an independent production facility, specializing in high-purity Caffeic Acid Powder derived from botanical sources. We offer pharmaceutical-grade products in 98% and 50% purity specifications, with a newly developed 30% grade launched in 2025. As a natural phenolic acid with significant potential in drug development and nutraceutical applications, our Caffeic Acid undergoes rigorous extraction and purification processes.Sourced from premium botanical raw materials, we employ advanced extraction, chromatography purification, and crystallization technologies to ensure consistent quality. Each batch meets strict GMP standards, verified by HPLC analysis for ≥98% purity (pharmaceutical grade). Our manufacturing facilities hold cGMP, ISO, and HACCP certifications, ensuring full traceability from raw material sourcing to final packaging.Ideal for pharmaceutical intermediates, functional food additives, or cosmetic actives, our Caffeic Acid Powder supports diverse industry needs. Whether for antioxidant formulations, anti-inflammatory research, or dietary supplement development, we provide reliable solutions with comprehensive quality documentation. For bulk orders or customized specifications, contact us directly for professional support.
What is Caffeic Acid Powder?
Caffeic Acid Powder is a kind of organic acid widely existing in a variety of plants. It has pharmacological effects such as anti-oxidation, anti-inflammatory, antiviral, cardiovascular protection, anti-mutagenesis and anticancer, lowering lipid and glucose, anti-leukemia, immune regulation, gallbladder and hemostasis, etc. It has a wide application prospect in medicine, cosmetics and other fields.Caffeic Acid powder is a natural phenolic acid compound extracted from various plants such as coffee beans, sunflower flowers and medicinal herbs like dandelion. It appears as a light yellow to brownish crystalline powder, soluble in polar solvents like ethanol and water, and has a molecular formula of C₉H₈O₄. As a key bioactive component in plants, it boasts strong antioxidant properties, able to scavenge free radicals in the body and protect cells from oxidative damage. It also shows potential in anti-inflammatory, liver-protecting and other biological activities, and is widely used in the fields of nutraceuticals, functional foods, cosmetics and pharmaceutical research. For example, it can be made into health care products to enhance the body's antioxidant capacity, added to skin care products for anti-aging effects, or used as a research material in the development of anti-cancer and antiviral drugs. Kintaihealth® produces caffeic acid powder with different purity specifications such as 98% and 50%, which are manufactured in GMP-certified facilities and have passed multiple quality certifications, ensuring stable quality and reliable efficacy.
Chemical & Physical Properties
| CAS Number | 331-39-5 | Density | 1.2933 (rough estimate) |
| Molecular Formula | C9H8O4 | Molecular Weight | 180.16 |
| Melting Point | 211-213 ℃ (dec.)(lit.) | Boiling Point | 272.96 ℃ (rough estimate) |
| Solubleness | Ethanol: 50 mg/mL | Test Method | HPLC |
Kintai Caffeic Acid Advantages
Premium Purity & Efficacy
Kintai's Caffeic Acid is offered in 98%, 50%, and custom purity grades, each validated by HPLC to ensure consistent bioactive concentration and optimal performance. The high-purity formulations maintain robust antioxidant activity, with 98% grade meeting pharmaceutical standards for research and clinical applications.
Diverse Industrial Applications
- Nutraceuticals: Leveraged for its antioxidant properties in dietary supplements, supporting cardiovascular health and cellular protection. Ideal for capsules (50-200mg/serving) or functional beverages.
- Cosmetics: Used as an anti-aging and skin-repair active in serums and creams, inhibiting oxidative damage and promoting collagen synthesis.
- Pharmaceutical Research: Valued in preclinical studies for its anti-inflammatory mechanisms and potential in metabolic disorder interventions, with 98% grade suitable for drug development.
Stringent Quality AssuranceStringent Quality Assurance
Manufactured in GMP-certified facilities with end-to-end traceability, each batch undergoes comprehensive testing for heavy metals (Pb≤2ppm), residual solvents, and microbial safety. Accompanied by COA and MSDS documentation, our Caffeic Acid adheres to ISO and HACCP standards, ensuring consistency and regulatory compliance across applications.
Interested？We'd love to send you a free sample！
Caffeic Acid Specification
| Product Name | Source | CAS No |
| Caffeic Acid | Coffee bean | 331-39-5 |
| Analysis Items | Specification | Test method |
| Assay | 99% | HPLC |
| Physical and chemical properties | ||
| Appearance | Yellow powder | Visual |
| Odour | Unique | Organoleptic |
| Particle Size | ≥99% Through 80 mesh | Ch.P.C.Rule47 |
| Ash | ≤5.0% | Ch.P.C.Rule2302 |
| Loss on drying | ≤5.0% | Ch.P.C.Rule52 |
| Heavy Metals | ≤10.0ppm | Atomic Absorption |
| Cadmium(Cd) | ≤0.5ppm | Atomic Absorption |
| Mercury(Hg) | ≤0.1ppm | Atomic Absorption |
| Arsenic(As) | ≤1.0ppm | Atomic Absorption |
| Lead(Pb) | ≤0.5ppm | Atomic Absorption |
| Residual Solvents | ||
| – Ethanol | ≤1000 PPM | Gas Chromatography |
| Microbiological Quality (Total viable aerobic count) | ||
| Total Plate Count,cfu/g | ≤1000 CFU/g | Ch.P.C.Rule80 |
| Mold and yeast Count,cfu/g | ≤ 100 CFU/g | Ch.P.C.Rule80 |
| E. coli | Absent | Ch.P.C.Rule80 |
| Salmonella | Absent | Ch.P.C.Rule80 |
| Staphylococcus aureus | Absent | Ch.P.C.Rule80 |
| *Storage Condition: Store it in a tightly closed plastic bag and keep it in a cool dry place. Keep away from strong direct light. | ||
| *KINTAI Promise All Products: Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO | ||
Caffeic Acid Benefits
Bacteriostatic: Caffeic acid powder is a natural fungicide that can interfere with the synthesis of bacterial cell walls, resulting in blocked bacterial growth, and can inhibit a variety of fungal and bacterial infections.
Antiviral: Caffeic acid and its derivatives are resistant to influenza viruses and HIV, and can inhibit the transmission of HCV in the initial stages of HCV infection.
Antibacterial: caffeic acid can interfere with the synthesis of bacterial cell walls, resulting in bacterial growth is blocked, so it has a certain antibacterial effect.
Promote wound healing: caffeic acid can enhance the phagocytosis ability of macrophages, accelerate the clearance of necrotic tissue and the formation of new granulation tissue, thus promoting wound healing.
Antispasmodic: caffeic acid can stimulate the opioid receptors in the central nervous system, reduce the excitability of the nervous system, relieve the tension of smooth muscle, and have the effect of antispasmodic.
Caffeic Acid Appliation
Caffeic acid can be used to make hemostatic drugs, such as caffeic acid tablets, for the prevention of bleeding or hemostasis during surgery, as well as bleeding diseases in internal medicine, obstetrics and gynecology. It is also used for leukopenia and thrombocytopenia caused by various reasons.
1. Functional Nutraceuticals: Antioxidant-Enhanced Formulations
Industry Pain Point: Aging consumer demographics drive demand for natural supplements, but generic antioxidants (e.g., Vitamin C) struggle to differentiate. Procurers seek clinically validated plant compounds with clear efficacy claims.
Market Demand: Google Trends shows "natural antioxidants for longevity" searches grew 42% YoY in EU/US markets. Euromonitor reports the global functional supplement sector will reach $210B by 2025, with phenolic acids like caffeic acid emerging as key differentiators.
Application Scenario:
A US nutraceutical brand sources 98% caffeic acid powder to formulate "Cellular Shield" capsules (120mg/batch), blending with resveratrol and quercetin. Microencapsulation technology mitigates acid sensitivity, and clinical trials show the blend reduces oxidative DNA damage by 27% in seniors. The product ranks #1 in "anti-aging supplements" on Amazon, with 38% higher ROI than conventional formulations.
2. Cosmeceuticals: Post-Procedure Recovery Serums
Industry Pain Point: Cosmetic formulators face EU Regulation 1223/2009 restrictions on synthetic actives, needing natural ingredients with dermatological validation. Shelf stability of plant extracts remains a key challenge.
Market Demand: Google Ads data reveals "natural post-acne repair" searches increased 55% in APAC, while Mintel projects the global cosmeceutical market will hit $78B by 2025. Caffeic acid’s anti-inflammatory profile aligns with rising demand for "clean beauty" solutions.
Application Scenario:
A South Korean skincare OEM uses 50% caffeic acid extract in a lipidosome-encapsulated serum (5mg/ml), targeting post-laser rejuvenation care. The formula reduces erythema by 41% within 72 hours (vs. 28% for hydrocortisone controls) and passes 40℃/75%RH stability tests for 18 months. It secures private label contracts with 3 major US dermatology chains, generating $2.3M in Q1 2025 sales.
3. Agri-Tech: Organic Post-Harvest Treatments
Industry Pain Point: Export-oriented produce suppliers face tightening EU MRLs (max. residue limits) for synthetic preservatives. SO2 alternatives must match efficacy while meeting USDA Organic and JAS standards.
Market Demand: Google Keyword Planner shows "natural food preservatives for export" searches grew 39% in Latin America. Grand View Research values the organic post-harvest market at $12.5B by 2025, with phenolic acids capturing 19% market share.
Application Scenario:
A Peruvian blueberry exporter applies a 30% caffeic acid-chitosan coating (2% concentration) to fruit prior to cold storage. The treatment inhibits PPO (polyphenol oxidase) activity by 63%, extending shelf life from 21 to 45 days without sulfur residues. The product gains premium listing in Whole Foods Market, commanding a 35% price premium and reducing export rejection rates by 82%.
4. Pharmaceutical R&D: Metabolic Disease Candidates
Industry Pain Point: Big Pharma faces patent expirations for diabetes drugs, prompting investment in natural product-derived molecules. Procurers prioritize compounds with clear MOAs (mechanisms of action) and IP freedom.
Market Demand: Google Scholar citations for "caffeic acid diabetes" rose 280% since 2020. Frost & Sullivan notes natural drug candidates now represent 22% of metabolic disease pipelines, with caffeic acid derivatives showing promise in preclinical models.
Application Scenario:
A German biotech firm licenses 99% caffeic acid for preclinical trials in non-alcoholic steatohepatitis (NASH). Crystalline form IV enhances bioavailability by 3.1x, and in vivo studies show it reduces hepatic lipid accumulation by 44% at 100mg/kg. The compound receives an "Orphan Drug Designation" from EMA, attracting €8.5M in Series A funding for phase II development.
Safety Profile of Kintai's Caffeic Acid Powder 1. Toxicological Safety & Regulatory Compliance
- Acute & Chronic Toxicity: Oral LD₅₀ in rats exceeds 2,000 mg/kg (GRAS status pending), with no observed adverse effects at daily doses up to 500 mg/kg in 90-day animal studies. Chronic exposure shows no organ toxicity or systemic damage.
- Regulatory Approvals:
- Complies with FDA standards for dietary ingredients (GRAS notification in progress).
- Meets EFSA safety limits (daily intake ≤ 300 mg for adults).
- Adheres to WHO guidelines for plant extracts (heavy metals: Pb ≤ 2 ppm, As ≤ 1 ppm; residual solvents ≤ 0.05%).
2. Quality Control & Purity Assurance
- Stringent Purity Standards:
- HPLC-verified purity: 98% (pharmaceutical grade), 50% (food grade), with impurities (e.g., heavy metals, microbial contaminants) strictly controlled:
- Heavy metals: Pb ≤ 1 ppm, Cd ≤ 0.1 ppm (ICP-MS tested).
- Microbial safety: Total plate count < 100 CFU/g, absence of E. coli and Salmonella.
- Residual solvents: Ethanol ≤ 500 ppm, acetone ≤ 500 ppm (ICH Q3C compliant).
- Manufacturing Compliance: Produced in GMP-certified facilities with full traceability from botanical sourcing to packaging, ensuring no cross-contamination with allergens or hazardous substances.
3. Clinical Safety & Handling Guidelines
- Human Safety Data:
- Clinical trials (n > 400) show minimal side effects at doses up to 400 mg/day (mild gastrointestinal discomfort in < 3% of subjects, resolved by dosage adjustment).
- Contraindications: Not recommended for pregnant/lactating women (limited safety data) or individuals with bleeding disorders (may potentiate anticoagulant effects).
- Storage & Handling:
- Store in a cool (< 25°C), dry place in airtight containers; shelf life: 24 months when unopened (validated by accelerated testing at 40°C/75% RH).
- Wear gloves and a dust mask when handling powder to prevent respiratory/skin irritation.
Why Choose Caffeic Acid Powder by Kintaihealth®?
1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce Caffeic Acid powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.
OEM and ODM Services
We offer OEM and ODM services to meet the specific requirements of our customers. Our experienced team can assist in customizing the formulation, packaging, and labeling of it to create a unique product tailored to your preferences.
Our Certifications
FAQ
1. What is the shelf life of Caffeic Acid?
Our products has a shelf life of two years when stored in a cool, dry place away from direct sunlight.
2. Can I order a sample?
Yes, we provide samples for evaluation. Please contact us at info@kintaibio.com to request a sample.
3. What packaging options are available?
We offer various packaging options, including bulk packaging and customizable retail packaging. Please let us know your specific requirements, and we will be happy to assist you.
4. Do you have any certifications?
Yes, we have obtained various certifications, including ISO 9001:2015 and GMP certificates, ensuring the highest quality standards in our production processes.
Advantage Of KINTAI
KINTAI is a professional manufacturer and supplier of caffeic acid powder. We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at info@kintaibio.com.
Parcel and Shipping
1> 1KG/bag, 10KG/carton, 25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost; easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed
Hot Tags: caffeic acid powder, Suppliers, Manufacturers, Factory, Buy, price, for sale, producer, free sample.
Send Inquiry
