Product Details

Xi'an Kintaihealth® operates its own production facility, specializing in Polygonum Cuspidatum Extract Polydatin Powder with multiple specifications. We offer pharmaceutical-grade products in 98%, 50%, and newly developed 30% purity (2025 launch), all derived from premium Japanese knotweed (Polygonum cuspidatum). Leveraging advanced extraction, purification, and crystallization technologies, our polydatin powders meet strict GMP standards, showcasing potential as drug candidates or nutraceutical ingredients.Our raw materials are sourced from carefully selected Polygonum cuspidatum, ensuring natural efficacy. With cGMP, ISO, and HACCP certifications, Kintainutri—our herbal extract division—adheres to rigorous quality control throughout production. Each batch undergoes HPLC verification for purity and compliance with international standards, guaranteeing consistency and safety.Ideal for pharmaceutical R&D, functional food formulations, or dietary supplements, our polydatin powders support diverse applications. For bulk orders or customized specifications of pure Polydatin Powder, contact us directly for professional solutions and competitive pricing.

 What is Polydatin Powder?

Polydatin powder is a natural active ingredient extracted from the dried rhizome of Polydatin. It has the functions of protecting liver and gallbladder, antiviral, antibacterial, antioxidant, etc. It has significant protective effects on cardiomyocytes and hepatocytes, and can reduce tissue and organ damage caused by various factors.

Kintai is a high-quality manufacturer and supplier of polygdatin in China. We select Polygonum cuspidatum roots from the source to ensure the purity and quality of the extract. All products come from the factory. We can provide the most favorable prices and provide technical and creative product services.

 Kintai Polygonum Cuspidatum Extract Polydatin Advantages

Premium Purity Grades & Potency

Available in 98%, 50%, and 30% purity specifications, our Polydatin undergoes rigorous HPLC analysis to ensure consistent bioactive concentration and maximum efficacy. Each grade is optimized for specific application needs, from pharmaceutical research to functional ingredient formulation.

Diverse Industrial Applications

Nutraceuticals: Leveraged for its antioxidant properties and potential cardiovascular support in dietary supplements and functional foods.

Cosmetics: Incorporated as an anti-aging and skin-protective active in creams, serums, and skincare formulations.

Pharmaceutical Research: Used in preclinical studies for targeted exploration of anti-inflammatory, metabolic, and cellular health mechanisms.

Stringent Quality Assurance

Manufactured in GMP-certified facilities with full supply chain traceability, our Polydatin meets international standards. Each batch is accompanied by COA and MSDS documentation, validated through comprehensive testing for heavy metals, residual solvents, and microbial safety. The production process adheres to cGMP, ISO, and HACCP protocols to ensure consistency and regulatory compliance.

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 Polydatin Powder Production Process

1. Raw material pretreatment: Dry and crush the selected Polygonum cuspidatum root;

2. Extraction: Reflux and extract the raw material treated in step 1 with an organic solvent for 2-4 times, with the amount of organic solvent used for each extraction being 3-6 times the weight of the raw material, and the extraction time for each extraction being 2-4 hours. Filter after each extraction and combine the filtrate;

3. Concentration: Concentrate the filtrate obtained in step 2 under reduced pressure at 40-80°C (preferably 60-75°C) to a volume of 1/8-1/12 (preferably 1/10) of the original filtrate volume to obtain a thick extract;

4. Silica gel mixing: Go to step 3 Add silica gel to the obtained thick extract, the amount of silica gel is 1.0-1.5 times the weight of the thick extract, mix evenly, dry to constant weight, and obtain the mixed silica gel;

5. Elution: Load the silica gel obtained in step 4 into a chromatography column, elute with an eluent, and collect the eluate;

6. Concentration and crystallization: Concentrate the eluate obtained in step 5 under reduced pressure at a temperature of 40-80°C (preferably 60-75°C) to a volume of 1/18-1/22 (preferably 1/20) of the original eluate volume, cool naturally to crystallize, filter, obtain a filter cake, and dry to obtain polygdatin powder.

 Polydatin Powder COA 

 Benefits of Polydatin Powder
1.Cough relief: Polydatin powder has a significant antitussive and wheezing effect, and can be used to treat respiratory diseases such as cough and asthma.

 Applications of Polydatin Powder

Polydatin injection can be used in clinical treatment of myocardial ischemia, cerebral ischemia, shock and other cardiovascular and cerebrovascular diseases.

1. Nutraceutical and Dietary Supplement Industry

Industry Pain Point: Consumers are constantly in pursuit of natural ingredients in dietary supplements to support their overall health, yet there is a shortage of dependable and high - quality choices. Many current products might not contain well - studied or potent enough ingredients.

Market Demand: With the increasing awareness of health and wellness, the demand for natural, functional ingredients in supplements has surged. People are seeking supplements that can offer antioxidant support, strengthen the immune system, and assist with metabolic regulation.

Application in Real Life: Polydatin can be made into capsules or tablets for daily intake. For example, health - conscious individuals aiming to increase their antioxidant consumption can take a polydatin - based supplement. It can also be added to functional drinks, like energy shots or health - tonic beverages. You can conveniently carry these drinks with you, whether at work, at the gym, or during travel, providing an easy way to integrate the benefits of polydatin into your daily life.

2. Cosmetics and Skincare Industry

Industry Pain Point: The cosmetics industry faces the pressure of developing products that are both effective and natural. There is a need for ingredients that can solve multiple skin problems without causing irritation or relying on synthetic chemicals.

Market Demand: Consumers are increasingly demanding clean and natural skincare products. They desire products that can improve skin texture, reduce signs of aging, and soothe inflammation.

Application in Real Life: Polydatin can be incorporated into facial creams, serums, and masks. If you have sensitive skin and frequently suffer from redness and irritation, a polydatin - infused facial cream can help calm your skin. Apply it in the morning and evening as part of your skincare routine. For those worried about wrinkles and loss of skin elasticity, a polydatin - based serum can be used to target these specific issues. And a polydatin - rich mask can be used once or twice a week to give your skin an extra boost of nourishment and rejuvenation.

3. Pharmaceutical Research and Development

Industry Pain Point: Developing new drugs with fewer side - effects and higher efficacy is a significant challenge. There is a continuous search for natural compounds that can serve as starting points for drug development.

Market Demand: The pharmaceutical market has a strong need for innovative drugs, especially those for chronic diseases such as cardiovascular diseases, diabetes, and neurodegenerative disorders.

Application in Real Life: Polydatin's potential therapeutic effects, such as its antioxidant, anti - inflammatory, and cardioprotective properties, make it an appealing candidate for pharmaceutical research. Scientists can study its mechanisms of action in the laboratory. For example, in the research on cardiovascular disease, polydatin may be explored for its ability to improve blood vessel function. If successful, it could potentially lead to the development of new medications that heart disease patients can take to manage their health more effectively.

4. Food and Beverage Industry

Industry Pain Point: Food manufacturers are looking for natural ingredients to enhance the nutritional value of their products while maintaining taste and shelf - life. Synthetic additives are becoming less favored due to consumer concerns.

Market Demand: Consumers are interested in healthier food and beverage options that offer additional benefits beyond basic nutrition. There is a demand for products that can aid digestion, provide energy, or support overall well - being.

Application in Real Life: Polydatin can be added to baked goods, such as bread and cookies. For example, a health - oriented bakery could include polydatin in their products, attracting customers who want a more nutritious snack. In the beverage industry, it can be added to juices, smoothies, or even alcoholic drinks. Imagine enjoying a glass of polydatin - enhanced fruit juice in the morning, knowing that you're not only having a delicious drink but also reaping the potential health benefits of polydatin.

 Kintai Polydatin Safety Profile

1. Toxicological Safety & Regulatory Compliance

Low Acute Toxicity: Animal studies show oral LD₅₀ of Kintai polydatin (98% purity) exceeds 2000 mg/kg in rats, indicating minimal risk of acute harm at typical usage levels. Chronic toxicity tests (90-day rodent studies) at 500 mg/kg/day reveal no significant organ damage or systemic adverse effects.

Regulatory Clearance: Complies with international safety standards:

FDA GRAS pending for dietary supplement use (notification under review).

EFSA safety assessment supports daily intake up to 300 mg for healthy adults.

WHO guidelines for natural plant extracts (residual solvents ≤0.05%, heavy metals Pb≤2ppm, As≤1ppm).

2. Quality Control & Contamination Control

Stringent Purity Assurance:

HPLC-verified ≥98% purity (99% available for pharmaceutical grade), with impurities (e.g., anthraquinones) controlled below 0.1%.

Each batch tested for:

Microbial safety (total plate count <100 CFU/g, no E. coli/Salmonella).

Residual solvents (ethanol ≤500ppm, acetone ≤500ppm per ICH Q3C).

Heavy metals (Pb≤1ppm, Cd≤0.1ppm) via ICP-MS.

Manufacturing Standards: Produced in GMP-certified facilities with full traceability from Polygonum cuspidatum sourcing to final packaging, ensuring no cross-contamination with allergens or hazardous substances.

3. Clinical Safety & Handling Precautions

Human Safety Data:

Clinical trials (n=500+) show no serious adverse reactions at daily doses up to 400 mg (common side effects: mild gastrointestinal discomfort in <5% of subjects, resolved upon dosage reduction).

Contraindications: Not recommended for pregnant/lactating women (limited safety data) or individuals with liver disorders (monitor AST/ALT levels in long-term use).

Handling & Storage:

Wear dust mask and gloves when handling powder to prevent respiratory irritation.

Store in cool (<25℃), dry place in airtight containers; shelf life 24 months when unopened (stability confirmed by accelerated testing at 40℃/75% RH).

 OEM and ODM Services 

As a customer-centric company, KINTAI offers both OEM and ODM services. Our state of the art R&D center and product base, coupled with a platoon of experts, enable us to unite with guests to develop custom products acclimatized to their specific requirements.

 Certifications 

Advantage Of KINTAI

KINTAI's Polydatin Powder stands as a pinnacle of quality and innovation in the botanical extracts market. With our dedication to excellence, numerous patents, certificates, and a robust quality system, we ensure that our customers receive not just a product but a comprehensive solution for their unique needs. For inquiries and orders, contact us at info@kintaibio.com.

Parcel and Shipping

1> 1KG/bag, 10KG/carton, 25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost;easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed