Reishi Mushroom Polysaccharides

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China Manufacturers Best Suppliers supply Reishi Mushroom Polysaccharides for sale.

Xi'an Kintaihealth® is a leading producer of premium Reishi Mushroom Polysaccharides, delivering pharmaceutical-grade quality with purity consistently exceeding 98% through advanced extraction and purification technologies. As a key naturally-occurring bioactive compound (CAS: 9012-76-4), Reishi Polysaccharides exist in their core bioactive form, ensuring high bioavailability for diverse applications. Our GMP-compliant production process guarantees superior stability and reliability for use in immune-boosting functional foods that support systemic wellness, dietary supplements designed to enhance vitality and reduce fatigue, cosmeceuticals that improve skin hydration and elasticity through antioxidant properties, and pharmaceutical research focused on anti-tumor, anti-inflammatory, and immunomodulatory formulations.  If you want to buy Reishi Mushroom Polysaccharides, please contact us directly!

  What is Reishi Mushroom Polysaccharides?  

Reishi Mushroom Polysaccharides is one of the most effective components of Ganoderma lucidum, which is now particularly emphasized by pharmaceutical scientists and technologists. Ganoderma lucidum polysaccharide is safe and non-toxic, and it can be widely used in pharmaceutical, food and cosmetic industries. Ganoderma lucidum polysaccharides have a wide range of pharmacological activities, which can enhance the body's immunity, improve the body's ability to withstand hypoxia and eliminate free radicals.

Therefore, Ganoderma extract powder is widely used as an ingredient in various health products. ⁤ ⁤The extraction process for this powder includes deionized water and is prepared through a process certified by leading institutions with referenceable industry standard certifications. ⁤

  Kintai Reishi Mushroom Polysaccharides Advantages  

High Potency & Clinically Proven Efficacy : Our Reishi Mushroom Polysaccharides are available in Pharmaceutical Grade (≥98% purity) and Nutraceutical Grade (≥95% purity), rigorously analyzed by HPLC to ensure exceptional immunomodulatory, antioxidant, and anti-inflammatory properties. Every batch guarantees consistent bioactivity, enabling the development of premium - grade products.

Multi - Industry Application:
• Nutraceuticals: Immune - boosting agent, supports stress adaptation, and aids in fatigue reduction for dietary supplements.
• Cosmetics: Enhances skin hydration, reduces oxidative damage, and promotes a radiant complexion as a key ingredient in skincare formulations.
• Pharmaceuticals: Potential applications in research for anti - tumor, neuroprotective, and metabolic disorder - related therapies.

Strict Quality Control : Manufactured in a GMP - compliant facility, our Reishi Mushroom Polysaccharides offer complete traceability, accompanied by detailed COA, MSDS, and comprehensive testing for heavy metals, residual solvents, and microbial contaminants.

  Reishi Mushroom Polysaccharides Production Process  

Reishi Mushroom Polysaccharides can be extracted from Ganoderma lucidum spore powder or the substrate of Ganoderma lucidum. The extraction process usually includes steps such as pulverizing the substrate, adding a small amount of culture medium for fermentation, centrifugation of the raw material after fermentation, low-temperature vacuum concentration of the supernatant, dialysis, ethanol precipitation, acetone washing, de-proteinization, spray drying, etc., and finally mixing with 10% aqueous extracted dry powder. In addition, the extraction of polysaccharides from Ganoderma lucidum mycelium requires operations such as mycelium pretreatment, hot water extraction of polysaccharides, polysaccharide purification, and polysaccharide purity identification.

1. Raw Material Selection & Preprocessing

• Mushroom Cultivation: Premium Ganoderma lucidum mushrooms are cultivated under controlled conditions (temperature, humidity, and nutrient substrates) to ensure consistent polysaccharide content.

• Harvest & Drying: Mature fruiting bodies or mycelia are harvested at peak polysaccharide concentration, then air-dried or freeze-dried to preserve bioactivity.

• Crushing & Screening: Dried materials are crushed into fine powder and screened to remove impurities, ensuring uniform particle size for efficient extraction.

2. Extraction of Polysaccharides

• Water-Based Extraction: The standard method involves boiling mushroom powder in water under high temperature (80–100°C) for 2–4 hours to solubilize water-soluble polysaccharides. Pressurized extraction may enhance yield.

• Alcohol Precipitation: The extracted solution is filtered, concentrated via vacuum evaporation, and mixed with ethanol (60–80% concentration) to precipitate polysaccharides from the solution.

• Enzymatic Assistance: Cellulase or protease may be added during extraction to break down cell walls, improving polysaccharide release and purity.

3. Purification & Refinement

• Debris Removal: The precipitated polysaccharides are centrifuged or filtered to remove residual proteins, pigments, and small molecular impurities.

• Dialysis: Semipermeable membranes are used to separate low-molecular-weight compounds, ensuring only high-molecular-weight polysaccharides remain.

• Chromatographic Purification: Column chromatography (e.g., DEAE-cellulose or Sephadex) may be applied to isolate specific polysaccharide fractions based on charge or molecular size.

4. Drying & Formulation

• Spray Drying: The purified polysaccharide solution is spray-dried at low temperatures to form a fine powder, preserving thermal-sensitive bioactivity.

• Freeze Drying (Lyophilization): For higher-purity products, freeze-drying is used to minimize degradation, resulting in a porous powder with excellent solubility.

• Blending & Granulation: Depending on application needs, polysaccharides may be blended with excipients or granulated for optimal flowability in dietary supplements.

5. Quality Control & Testing

• Purity Analysis: HPLC or UV spectroscopy verifies polysaccharide content (≥95% for nutraceutical grade, ≥98% for pharmaceutical grade), while FT-IR confirms structural integrity.

• Contaminant Screening: Heavy metals (lead, arsenic), residual solvents, microbial counts (e.g., E. coli, Salmonella), and pesticide residues are tested to meet GMP standards.

• Bioactivity Assay: In vitro tests (e.g., immune cell activation, antioxidant capacity) ensure the polysaccharides maintain therapeutic properties.

  Reishi Mushroom Polysaccharides COA

   Reishi Mushroom Polysaccharides Benefits  

Reishi Mushroom Polysaccharides is one of the most active components of Ganoderma lucidum, which has a variety of pharmacological activities and effects:

 1. Immunomodulation: Ganoderma lucidum polysaccharides can stimulate the body's immune system and enhance the activity and function of immune cells, thus helping to improve the body's immunity and resistance to diseases.

 2. Antioxidant: Ganoderma lucidum polysaccharides have certain antioxidant ability, which can remove free radicals in the body and protect the integrity of cell structure and function, thus delaying aging and preventing the occurrence of many chronic diseases.

 3. Liver protection: Ganoderma lucidum polysaccharide can reduce the inflammatory reaction and damage of the liver, promote the repair and regeneration of liver cells, play a protective role for the liver, which is of some significance for the prevention and treatment of some liver diseases.

4. Regulation of blood sugar and blood lipid: Ganoderma lucidum polysaccharides can regulate blood sugar and blood lipid levels and improve metabolic disorders through various pathways, which is helpful for the prevention and control of metabolic diseases such as diabetes and hyperlipidemia.

  Reishi Mushroom Polysaccharides Applications  

Pharmaceutical application : Due to the unique physiological activity and clinical effect of Ganoderma lucidum polysaccharides and its safety and non-toxicity, it can be widely used in the pharmaceutical industry.

Food application : Ganoderma lucidum polysaccharides as functional factors can be made into health food, and can also be added as food additives into beverages, pastries and oral liquids, which have greatly enriched the food market.

Cosmetic application : Due to its anti-free radical effect, Ganoderma lucidum polysaccharides can be used in cosmetics to slow down the aging process.

Daily consumption : Ganoderma lucidum polysaccharide can be added into daily diet in many ways, such as Ganoderma lucidum polysaccharide powder can be added into drinks such as water, juice, soymilk, yogurt, etc.; it can be brewed with hot water for drinking; and it can be boiled in soups or cooked together with ingredients such as chicken, pork and pork ribs.

  Reishi Mushroom Polysaccharides Dosage  

It is recommended to purchase GMP-certified high-purity products (≥95%) and confirm the polysaccharide content and safety indicators (such as heavy metals, microbial residues) through HPLC test reports.

  Safety of KINTAI’S Reishi Mushroom Polysaccharides  

1. Allergic Reactions and Sensitivities

Reishi mushroom polysaccharides are generally safe for most users. However, individuals with known allergies to Ganoderma lucidum mushrooms, fungi, or related plant families may be susceptible to adverse reactions. An initial sensitivity test is recommended, especially when incorporating the polysaccharides into new dietary products. Discontinue use immediately and seek medical advice if symptoms like rash, itching, or respiratory discomfort occur.

2. Safety and Toxicity Research

• General Safety Limits: Clinical studies typically use doses of 100–600 mg/day without severe side effects. Doses exceeding 800 mg/day may cause mild gastrointestinal issues (e.g., bloating, diarrhea).

• Toxicity Data: Animal studies show the acute oral LD₅₀ of Reishi polysaccharides exceeds 2,000 mg/kg, indicating low acute toxicity. Long-term trials (up to 12 months) at 300–600 mg/day report no systemic toxicity.

• Purity and Quality: Kintai’s Reishi Mushroom Polysaccharides achieve pharmaceutical-grade purity (≥98%) via HPLC-verified extraction. Rigorous testing ensures minimal heavy metals, residual solvents, and microbial contaminants.

3. International Compliance

• EU Regulations: Approved for food supplements and nutraceuticals when meeting EU purity and safety standards.

• US FDA: As a dietary supplement, it falls under general GMP guidelines for manufacturing and safety.

• Asia: Licensed for use in dietary supplements, functional foods, and cosmeceuticals in China, Japan, and South Korea, adhering to local quality benchmarks.

Note: Pregnant/lactating women, children, and individuals with autoimmune diseases should consult a healthcare professional before use. Kintai’s products comply with global safety regulations to ensure consistent quality and reliability.

OEM and ODM Services：Customize Reishi Mushroom Polysaccharides with our OEM and ODM services. Benefit from our state-of-the-art R&D center, production base, and cutting-edge equipment. We offer one-stop solutions for your specific needs, ensuring high-quality and tailored products.

  Frequently Asked Questions  

Q1: What distinguishes KINTAI's pro?

A1: Our commitment to quality, advanced extraction methods, and a comprehensive approach to product customization set us apart.

Q2: Can these polysaccharides be used in combination with other supplements?

A2: Yes, It is versatile and can be seamlessly integrated into various formulations.

Q3: Are there any allergens in your product?

A3: Our extraction process ensures minimal allergen presence, and our products are tested to meet stringent quality standards.

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