Corosolic Acid Banaba Leaf Extract

Corosolic acid (CRA), a natural pentacyclic triterpenoid compound, is a unique active ingredient in Banaba leaf extracts. In addition, it is also found in a variety of plants, such as cranberry, loquat, perilla, weigela, and scutellaria.

Healthkintai^® Corosolic Acid Banaba Leaf Extract is derived from high-quality Banaba leaves. The powder is brown-green in color and has a unique Banaba leaf flavor. It is mainly used as a drug for the prevention and treatment of obesity and type 2 diabetes and a raw material for health foods. We stand out with high-quality raw materials, exquisite processing technology and high customer service. Our Corosolic Acid Banaba Leaf Extract has consistent quality. Please feel free to contact us at health

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Corosolic Acid Banaba Leaf Extract (CA) is an ursane-type pentacyclic triterpenoid compound, often existing in free or saponin form. Studies have shown that CA activates glucose transport, promotes cellular glucose absorption and utilization, and lowers blood sugar. CA exhibits multiple biological activities, including anti-tumor, anti-inflammatory, antioxidant, and antibacterial properties, and possesses promising development potential and broad application prospects. Studies have found that CA can downregulate mitogen-activated protein kinase (MAPK) activation, including phosphorylation of p38MAPK and ERK1/2, inhibiting mesangial cell proliferation and potentially treating DM-induced renal damage. This suggests that CA could be developed as a natural anti-DN agent. 

1.Excellent Blood Sugar Lowering and Antidiabetic Potential

Corosolic acid's most notable benefit is its potent blood sugar-lowering effect. Known as the "plant insulin," it regulates blood sugar levels through multiple pathways. Its primary mechanism is activation of the glucose transporter GLUT4, promoting cellular glucose uptake and utilization, thereby improving insulin sensitivity and reducing insulin resistance. For patients with type 2 diabetes or those with elevated blood sugar levels, Banaba Leaf Extract can effectively help control postprandial blood sugar and reduce the burden on the pancreas, making it a highly promising natural adjunct to hypoglycemics.

2.Effective Anti-Obesity and Lipid Metabolism Regulators

Corosolic acid also demonstrates promising anti-obesity effects. Studies have shown that it can inhibit adipocyte differentiation and fat accumulation, reducing triglyceride levels. Furthermore, Banaba Leaf Extract can activate the AMPK signaling pathway, a key regulator of cellular energy metabolism. This pathway promotes fatty acid oxidation and energy expenditure, thereby aiding weight control and reducing body fat, potentially contributing to the prevention and improvement of obesity and related metabolic syndromes.

3.Powerful Antioxidant and Anti-Inflammatory Capabilities

Corosolic acid is a polyphenolic compound with significant antioxidant activity, effectively scavenging free radicals in the body and reducing cellular damage caused by oxidative stress. Furthermore, it inhibits the production of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and regulates inflammatory signaling pathways such as NF-κB, thereby exerting anti-inflammatory effects. This is crucial for preventing chronic inflammatory diseases, delaying aging, and protecting organs from oxidative damage.

4.Potential Anti-Tumor and Anti-Cancer Activity

Recent studies have revealed that corosolic acid exhibits promising anti-tumor potential. Its mechanisms include inducing apoptosis (programmed cell death) in cancer cells, inhibiting cancer cell proliferation and angiogenesis, and preventing cancer cell invasion and metastasis. Although current research has primarily focused on in vitro and animal studies, results have shown that Banaba Leaf Extract has inhibitory effects on various cancer cell lines, including breast, colon, and lung cancer, providing research direction for its use as a natural anti-cancer adjuvant.

​​​​​​​​​​​​​​1. Diabetes Management and Blood Sugar Regulation

Corosolic acid is a natural anti-diabetic active ingredient whose core application is blood sugar regulation. It activates the glucose transporter GLUT4, significantly promoting glucose uptake and utilization by fat and muscle cells, thereby effectively lowering blood sugar levels. This mechanism is similar to the function of insulin, earning it the nickname "plant insulin." For patients with type 2 diabetes or prediabetes, corosolic acid can be used as a natural dietary supplement to help regulate insulin resistance and stabilize postprandial blood sugar.

2. Antioxidant and Skin Protection

As a natural antioxidant, Banaba Leaf Extract effectively scavenges free radicals, inhibits lipid peroxidation, and mitigates cellular damage caused by oxidative stress. This property has led to its widespread use in skincare and cosmetics. Skincare products containing corosolic acid can help delay skin aging, reduce wrinkles, improve skin elasticity, and protect skin cells from environmental damage such as UV rays, offering multiple benefits: whitening, moisturizing, and anti-aging. 3. Anti-inflammatory and Antibacterial Activity:Banaba Leaf Extract exhibits significant anti-inflammatory effects, inhibiting the production of key inflammatory factors such as TNF-α and IL-6, as well as the expression of inflammatory mediators such as COX-2. This makes it promising for applications in alleviating chronic inflammation and atopic dermatitis. Furthermore, it exhibits inhibitory effects against a variety of bacteria and fungi, making it a promising candidate for use in the development of natural preservatives or oral care products to help inhibit cariogenic bacteria and maintain oral health.

4. Anti-obesity and Lipid-Lowering Effects

Corosolic acid exhibits significant potential for weight management and lipid metabolism. Studies have shown that it can inhibit the differentiation of preadipocytes, reducing fat production and accumulation. Furthermore, corosolic acid can activate the AMPK signaling pathway, enhance fatty acid β-oxidation, and accelerate fat breakdown, thereby lowering triglyceride and total cholesterol levels. This property makes it a promising candidate ingredient for the development of natural and safe weight loss products, potentially helping to prevent and control obesity and related metabolic syndromes.

5. Anti-tumor Potential and Auxiliary Applications

Recent studies have shown that Banaba Leaf Extract exhibits some anti-tumor activity. It can inhibit a variety of cancer cells, including breast cancer, colon cancer, and liver cancer, by inducing apoptosis, inhibiting proliferation and metastasis, and blocking the cell cycle. Although still primarily in the research stage, Corosolic Acid Banaba Leaf Extract provides new direction and scientific basis for the development of natural anti-cancer auxiliary drugs or health foods with low toxicity and side effects.

• High Standards: Kintai's Crape Myrtle Leaf Extract strictly adheres to international pharmacopoeia standards and utilizes advanced chromatographic technology to ensure high purity, stable active ingredient content, and excellent batch-to-batch consistency, providing a core guarantee for product safety and efficacy.
• Professional Team: Led by experienced botanists and pharmacologists, our R&D team possesses extensive industry experience and innovative R&D capabilities, providing comprehensive technical support and customized solutions from cultivation to extraction.
• Multiple Applications: Research has confirmed that this extract can be widely used in pharmaceuticals, functional foods, and high-end skincare products, meeting diverse market needs for antioxidant, anti-glycation, and anti-inflammatory properties, demonstrating significant commercial potential.

1.Q: Is Corosolic Corrosive Banaba Leaf Extract ok for everyday utilization?

   A: The extract is for the most part for everyday utilization. Be that as it may, people are urged to stick to suggested measurements and talk with a medical services professional if necessary.

2.Q: What is corosolic acid good for?

   A: 1. Supports healthy blood sugar levels

     2. Boosts metabolism and weight management

     3. Antioxidant and anti-inflammatory effects

3.Q: What is corosolic acid side effects?

   A: Generally, it is safe, but some people may experience mild gastrointestinal discomfort.
Pregnant women, breastfeeding women, people with hypoglycemia or those taking hypoglycemic drugs should use it with caution. It is recommended to consult a doctor before use.