What is taxifolin used for?
2024-09-24 09:37:57
Taxifolin(TAX), commonly known as dihydroquercetin(DHQ), is a natural water-soluble flavonoid compound. It is primarily extracted from the rootstock or heartwood of the Russian larch tree and is also found in small quantities in citrus fruits. As a direct derivative of quercetin, Taxifolin is renowned for its exceptional antioxidant capacity, effectively neutralizing free radicals and suppressing inflammation. Its unique molecular structure grants it significantly higher bioavailability than quercetin.

Healthkintai is a leading manufacturer and supplier of dihydroquercetin in China. We can provide you with 98% high-quality dihydroquercetin. For more product details, please contact us at health@kintaibio.com.
What is Taxifolin?
Taxifolin, also known as dihydroquercetin, is a potent natural flavonoid belonging to the subclass of flavanonols. It is a direct hydrogenated derivative of the well-known antioxidant quercetin, but with a distinct chemical structure that grants it unique properties. This compound is primarily sourced from the heartwood and rootstock of coniferous trees like the Siberian larch (Larix sibirica) and the Douglas fir.
Renowned for its powerful antioxidant activity, DHQ effectively scavenges free radicals and combats oxidative stress at the cellular level. Its key advantage lies in its superior bioavailability compared to quercetin, owing to its molecular configuration that allows for better absorption. Scientific research highlights its notable benefits in supporting liver health by protecting it from chemical-induced damage and promoting detoxification processes. Furthermore, it contributes to cardiovascular wellness and is increasingly valued in advanced skincare for its ability to protect the skin matrix and support collagen synthesis.

Due to these efficacy and absorption benefits, taxifolin is a premium ingredient in high-end nutraceuticals for liver support and elite cosmeceutical formulations aimed at anti-aging and skin vitality.
Taxifolin for Cardiac Function
Heart failure (HF) is a heterogeneous syndrome caused by impaired ventricular filling or ejection function. It is the end-stage of various heart diseases, with high morbidity and mortality, and has become a serious public health problem affecting people's health. DHQ can protect myocardial ischemia-reperfusion injury and prevent diabetic cardiomyopathy by inhibiting oxidative stress, regulating endoplasmic reticulum stress, and mitochondrial apoptosis pathways. It can also improve myocardial cell hypertrophy by reducing mitochondrial dysfunction and glucose metabolism disorders, and has a certain ameliorative effect on myocardial hypertrophy and myocardial fibrosis after stress overload.

(Reference:Protective Effect and Its Mechanism of Dihydroquercetin on Cardiac Function in Rats with Heart FailureSUN Chunmei, TANG Ling, TUO Yuping)
Benefits of Taxifolin
1. Antioxidant and Anti-inflammatory Effects
As a powerful natural antioxidant, Taxifolin effectively neutralizes free radicals and reduces oxidative stress-induced cell damage, with capabilities considered superior to its precursor, quercetin.
It can effectively reduce tissue inflammation by inhibiting key inflammatory pathways such as NF-κB, potentially improving chronic inflammation-related diseases.
2. Liver Protection
This is one of Taxifolin's most prominent benefits. Dihydroquercetin effectively combats liver damage caused by alcohol, drugs, and chemicals by enhancing the activity of liver detoxification enzymes, inhibiting hepatic stellate cell activation, and protecting hepatocyte membranes, and helps slow the progression of liver fibrosis.
3. Cardiovascular Health Support
Taxifolin helps improve lipid metabolism and lower low-density lipoprotein (LDL) cholesterol levels.
It protects vascular endothelial cells, improves microcirculation, and, through DHQ's anti-inflammatory and antioxidant properties, slows the development of atherosclerosis, thus comprehensively supporting the cardiovascular system.
4. Promotes Skin Health and Anti-Aging
In the skincare field, TAX is highly favored due to its high bioavailability. Dihydroquercetin protects the skin from UV-induced photoaging and effectively maintains skin elasticity and reduces wrinkles by promoting collagen synthesis and cross-linking, thus playing an anti-aging role.

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Taxifolin Side effects
|
Aspect |
Description |
|
Overall Safety |
Generally considered very safe and well-tolerated with a high safety profile. Studies indicate low toxicity. |
|
Common Side Effects |
Rare and typically mild. May include minor gastrointestinal discomfort (e.g., slight nausea, stomach upset). |
|
Serious Side Effects |
None have been reliably reported in clinical studies to date. |
|
Comparitive Tolerance |
Often better tolerated than its relative, quercetin, causing less gastrointestinal irritation. |
|
Key Considerations & Precautions |
- Pregnancy & Breastfeeding: Safety not established; consult a healthcare professional. |
KINTAI Tacfolin Advantages
- Natural Raw Materials: We select premium larch as our core plant source, ensuring the purity of our raw materials.
- Advanced Processing: Utilizing modern extraction and purification technologies, we guarantee high efficiency and consistent quality.
- Ultimate Purity: Our core products maintain a purity consistently above 98%, achieving industry-leading standards.
- Authoritative Certifications: Holding international certifications such as GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, and HALAL, we are safe and reliable.
- Low-Price: Thanks to large-scale production, our prices are highly competitive among similarly high-quality products.
If you want to know more details or get free samples of KINTAI DHQ,please feel free to contact us at health@kintaibio.com.

