Asiaticoside
CAS No: 16830-15-2
Specification: 10%~90%Asiaticoside
Appearance: White powder
Test Method: HPLC
Lead time: 1-3 days
Storage: Cool dry place and avoid light
Shelf Life: 2 years
MOQ: 1KG
Sample: Free sample available
Certifications: GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
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Product Introduction
Product Details
Xi'an Kintaihealth® stands as a leading producer of premium Asiaticoside powder (CAS: 16830-15-2). Through cutting-edge extraction and purification techniques, we provide pharmaceutical-grade products, maintaining Asiaticoside in its most bioactive state. This ensures optimal absorption and effectiveness across various applications. Our strict quality control measures guarantee consistency in purity and potency, making our Asiaticoside powder a reliable choice for industries seeking high-quality natural ingredients. Whether for use in skincare, pharmaceuticals, or dietary supplements, our product's superior bioavailability supports the development of top-tier formulations.
What is Asiaticoside Powder?
Asiaticoside, otherwise called madecassoside, is a characteristic triterpene glycoside obtained from Centella Asiatica, an enduring spice tracked down in Asia. It is known for its different medical advantages and restorative properties. It has been widely read for its expected applications in injury mending, skin revival, and mitigating impacts.
Asiaticoside Powder Properties
Product Name | Centella Asiatica extract Asiaticoside 90% powder | Latin Name | Centella asiatica (L.) |
---|---|---|---|
Appearance | White powder | Other Name | |
CAS No | 16830-15-2 | Molecular Formula | C48H78O19 |
Molecular Weight | Active ingredient | Asiaticoside | |
Specification | >90% | Origin | Guang Xi, China |
Part Used | Gotu Kola leaf | Test Method | HPLC |
MOQ | 1 KG | COA |
Kintai Asiaticoside Powder Advantages
High Potency & Clinically - Backed Efficacy
Kintai's Asiaticoside powder (CAS: 16830 - 15 - 2) delivers pharmaceutical - grade quality, with purity consistently exceeding 98% as verified by advanced HPLC analysis. Clinically recognized for its potent bioactivity, asiaticoside promotes collagen synthesis, accelerates wound healing, and exhibits strong anti - inflammatory and antioxidant properties. These attributes are supported by extensive research, ensuring reliable efficacy in various applications, from treating skin ulcers to reducing scar tissue formation. Each batch undergoes rigorous testing to maintain consistent bioactivity, providing a reliable ingredient for high - performance formulations.
Multi - Industry Application
· Cosmetics & Skincare: A key ingredient in anti - aging creams, serums, and wound - care products. It improves skin elasticity, reduces the appearance of fine lines, and enhances the skin’s natural repair process, making it ideal for post - surgical or burn scar management.
· Pharmaceuticals: Used in research and development for topical treatments targeting dermatitis, psoriasis, and other inflammatory skin conditions. Its antioxidant properties also position it as a potential component in drugs for preventing oxidative stress - related diseases.
· Dietary Supplements: Added to health products to support connective tissue health, joint function, and overall skin wellness, leveraging its collagen - boosting and anti - inflammatory benefits.
Strict Quality Control
Manufactured in a GMP - compliant facility, Kintai's Asiaticoside powder ensures end - to - end quality assurance. From carefully selected raw materials to the final product, each stage undergoes strict monitoring. Every batch comes with detailed Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), confirming compliance with international standards. Comprehensive testing for heavy metals, residual solvents, and microbial contaminants guarantees safety and purity, providing customers with a trustworthy, high - quality ingredient for their formulations.
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Manufacturing Process of Asiaticoside Powder
The production of asiaticoside involves raw material processing, extraction, purification, and drying, integrated with modern technologies to enhance purity and yield. Below are the key steps:
1. Raw Material Pretreatment
· Harvesting and Drying: Centella asiatica (Umbelliferae) is typically harvested in summer and autumn. The whole herb is washed, sun-dried or low-temperature dried, then cut into 1.5 cm segments for subsequent extraction.
· Grinding: In some processes, dried materials are ground into powder through an 80-mesh sieve to increase the extraction surface area.
2. Active Ingredient Extraction
· Solvent Extraction: Commonly, 65% ethanol is mixed with materials at a 10:1 volume ratio, reflux-extracted in a 55℃ water bath for 3 times (1.5 hours each), and the supernatant is combined after centrifugation. Some processes use complex enzymes (e.g., cellulase, pectinase) to assist in cell wall hydrolysis for higher extraction efficiency.
· Flash Extraction: Modern techniques may adopt rapid extraction (flash extraction) via high-temperature short-time treatment to accelerate active ingredient dissolution.
3. Purification and Concentration
· Macroporous Resin Adsorption: After 减压浓缩 (reduced-pressure concentration), the extract is passed through a macroporous resin column (e.g., XAD-3 or resin with a length-diameter ratio of 2:1 to 6:1). Impurities are washed off with deionized water, followed by gradient elution with 30%-70% ethanol, tracked by thin-layer chromatography (TLC) for target components.
· Membrane Separation Technology: Some processes introduce membrane systems to remove macromolecular impurities (e.g., pectin, tannins), preserving active ingredients and improving purity.
4. Drying and Finished Product Preparation
· Concentration and Drying: The eluent is concentrated under reduced pressure, then vacuum-dried to obtain light yellow to brownish-yellow asiaticoside powder, with industrial purity exceeding 95%.
· Solvent Recovery: Solvents like ethanol are recycled to reduce costs and environmental impact.
5. Quality Control
· Purity Detection: Analyzed by HPLC, some processes achieve a recovery rate of 86.24% and purity of 95.44%.
Asiaticoside Powder Benefits
This product advances collagen blend, which helps in injury recuperating and tissue recovery. It likewise has cancer prevention agent properties that safeguard the skin from harm brought about by free extremists. Also, it further develops blood course and fortifies the skin's boundary capability. It has shown promising outcomes in decreasing scars, stretch stamps, and kinks. Its calming properties make it successful in treating different skin conditions, including dermatitis and psoriasis.
1. Powerful Wound Healing Properties:Asiaticoside significantly accelerates wound healing by promoting collagen synthesis and enhancing the formation of new blood vessels. It stimulates fibroblast activity, which are key cells involved in tissue repair, helping to close wounds faster and reduce the risk of scarring. This makes it a valuable ingredient in post - surgical care products, as well as treatments for burns, cuts, and chronic skin ulcers.
2. Anti - Inflammatory and Antioxidant Effects:With strong anti - inflammatory capabilities, asiaticoside reduces inflammation by inhibiting the production of pro - inflammatory cytokines. It also acts as an antioxidant, neutralizing free radicals in the body. This dual action helps protect the skin from damage caused by oxidative stress, such as UV radiation and pollution, and can alleviate skin conditions like dermatitis, eczema, and psoriasis.
3. Skin Rejuvenation and Anti - Aging:By boosting collagen production, asiaticoside improves skin elasticity and firmness, reducing the appearance of fine lines and wrinkles. It also promotes skin cell turnover, giving the skin a smoother and more youthful appearance. Additionally, it can help fade age spots and hyperpigmentation, making it a popular ingredient in anti - aging skincare formulations.
4. Connective Tissue Health Support:Asiaticoside is beneficial for maintaining healthy connective tissues, including tendons, ligaments, and cartilage. It can enhance the strength and integrity of these tissues, making it useful in supplements for athletes to prevent injuries and aid in recovery. For individuals with joint problems, it may help reduce joint pain and improve mobility by supporting the health of the surrounding connective tissues.
5. Hair and Scalp Health Improvement:When applied topically or consumed as a supplement, asiaticoside can improve hair and scalp health. It promotes blood circulation in the scalp, which delivers essential nutrients to hair follicles, stimulating hair growth. Its anti - inflammatory properties also help soothe irritated scalps, reducing dandruff and itchiness.
Asiaticoside Powder Specifications
Product Name | Asiaticoside Powder |
---|---|
Appearance | White crystalline powder |
Purity | ≥ 98% |
Particle Size | 80-100 mesh |
Melting Point | 223-225°C |
Storage | Store in a cool and dry place |
Asiaticoside Powder Applications
Asiaticoside is a bioactive compound derived from Gotu Kola, and offers a wide range of applications across several industries. Its beneficial properties make it a valuable ingredient in the following sectors:
Cosmetics: It is profoundly esteemed in the makeup business for its skin-upgrading properties. It is generally utilized in skincare items, including creams, moisturizers, serums, and veils. It is known for its likely enemy of maturing impacts, as it advances collagen blend and further develops skin versatility. It likewise helps with decreasing the presence of barely recognizable differences, kinks, and age spots. Moreover, this item has skin-fixing benefits and can help alleviate and mend harmed skin.
Pharmaceuticals: It tracks down applications in the drug business because of its possible remedial impacts. It is often utilized in treatments and gels for wound recuperation and scar decrease. It has been read up for its capacity to improve the creation of collagen and advance tissue recovery, making it advantageous for treating consumes, cuts, and other skin wounds. Besides, it displays calming properties that can support diminishing irritation and advancing generally speaking skin well-being.
Healthcare: Asiaticoside powder bulk tends to be integrated into dietary enhancements for its general medical advantages. It is accepted to have disease prevention agents and calming properties, which might add to its potential well-being-advancing impacts. It is in many cases remembered for plans pointed toward supporting mental capability, diminishing pressure and uneasiness, and working on general prosperity.
It is critical to take note that while this product has shown promising outcomes in these applications, further exploration is yet progressing to comprehend its systems of activity and potential purposes completely.
Asiaticoside Powder Dosage Recommendation
Application Type | Dosage Range | Usage Frequency | Notes |
Topical (Creams/Serums) | 0.1%–2% concentration | 1–2 times daily | Patch test for sensitive skin; avoid eye contact. |
Oral Supplementation (General) | 60–120 mg/day | 2–3 divided doses | Suitable for daily health maintenance. |
Oral (Wound/Connective Tissue) | 120–240 mg/day | Under medical supervision | For enhanced tissue repair; short-term use (4–8 weeks). |
Therapeutic (Skin Disorders) | 150–300 mg/day | Divided doses | Combine with topical applications for eczema/dermatitis. |
Joint/Cartilage Health | 200–400 mg/day | Long-term use | Often paired with glucosamine; consult a professional. |
Pediatric (Under 12 years) | Not recommended | - | Insufficient safety data for children. |
Pregnant/Lactating Women | Consult healthcare provider | - | Limited research on safety during pregnancy/lactation. |
Individuals with Liver/Kidney Issues | Reduce dosage or avoid | - | Medical advice required to prevent organ stress. |
Safety of Kintai's Asiaticoside Powder
1. Toxicological Considerations
· Acute Toxicity: Asiaticoside (CAS: 16830-15-2) is a natural triterpenoid with low acute toxicity. Animal studies show oral LD₅₀ values > 2000 mg/kg in rodents, indicating minimal risk from accidental ingestion at standard doses. Kintai’s products undergo toxicity screening to ensure compliance with safety benchmarks.
· Chronic Exposure Risks: Prolonged exposure to high concentrations may cause mild skin irritation or gastrointestinal discomfort. Kintai’s quality controls limit residual solvents and impurities to minimize long-term risks.
2. Quality Control & Safety Certifications
· Purity Assurance:
· Pharmaceutical-grade (≥98% purity) and nutraceutical-grade (≥95%) verified by HPLC, with contaminant controls including:
· Heavy metals (Pb ≤3ppm, As ≤3ppm)
· Residual ethanol ≤5000ppm
· Microbial safety (total plate count ≤1000cfu/g, E. coli/salmonella negative)
· Manufacturing Standards:
· Produced in GMP-compliant facilities with batch-specific COA and MSDS, detailing handling protocols and safety data.
3. Handling & Storage Precautions
· Physical Hazards: Inhalation risk from powder; use in well-ventilated areas with gloves/mask.
· Storage: Store in a cool (≤25℃), dry place away from light and moisture to maintain stability.
· Disposal: Follow local regulations for chemical waste, especially solvent residues (e.g., ethanol).
4. Regulatory Compliance
· Meets international standards for food additives (FDA/EFSA), pharmaceuticals, and cosmeceuticals. Pharmaceutical-grade products align with ICH guidelines for active ingredient safety testing.
5. Safety Warnings & Limitations
· Contraindications: Avoid use during pregnancy/lactation without medical advice; limited safety data in sensitive populations.
· Adverse Reactions: Possible side effects include skin redness (topical) or nausea (oral); discontinue use if irritation occurs.
· Use Restrictions: Intended for research/industrial applications unless approved for specific human use (e.g., pharmaceutical formulations).
6. Key Safety Summary
Aspect | Detail |
Purity | ≥98% (pharmaceutical) via HPLC, with strict heavy metal/solvent controls. |
Toxicity Reference | LD₅₀ > 2000 mg/kg (rodents, oral); low acute toxicity profile. |
Regulatory Support | COA, MSDS, and GMP compliance provided for each batch. |
Cautionary Note | Consult a professional before use in therapeutic or pediatric applications. |
Why Choose Sanguinarine Powder by Kintaihealth®?
1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce sanguinarine powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.
Advantages Of KINTAI
OEM and ODM Services
KINTAI is a professional manufacturer and supplier of Asiaticoside Powder Bulk. We offer OEM and ODM services, allowing you to customize the product according to your specific requirements. Our research and development center, production base, and advanced equipment ensure the highest quality standards. We provide integrated service solutions, ensuring fast delivery and secure packaging.
FAQ
1. What is the recommended dosage of this product for skincare?
- The recommended dosage varies depending on the specific product and its intended use. It is advised to follow the instructions provided by the manufacturer.
2. Are there any side effects of this product?
- It is for the most part viewed as safe for effective and oral use. In any case, counseling a medical care proficient prior to utilizing any new item or supplement is constantly suggested.
3. Can Asiaticoside be used in combination with other skincare ingredients?
- It tends to be actually joined with other skincare fixings, for example, hyaluronic corrosive, L-ascorbic acid, and peptides, to upgrade its advantages and in general adequacy. Nonetheless, taking into account compatibility and proper formulation techniques is significant.
For more information about our products or to discuss your specific requirements, please contact us at health@kintaibio.com.
About KINTAI
Our Certifictions
Parcel and Shipping
KINTAI is a professional manufacturer and supplier of Asiaticoside Powder. We have a dedicated research and development center, state-of-the-art production base and equipment, multiple patents, certifications, and quality system accreditation. We specialize in customized products and offer integrated service solutions. With fast delivery and secure packaging, we are your trusted partner for this product. Contact us today!
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