Betulinic acid

Betulinic Acid(BA) is a pentacyclic triterpenoid compound, which is widely found in the natural world, and is mainly extracted from the bark of betula alba. By modifying the chemical structure of BA, a variety of derivatives can be obtained. Studies have shown that betulinic acid has many biological activities such as anti-inflammatory, antibacterial, anti-malaria, etc. In addition, BA also has a strong toxic effect on a variety of tumors, but has no lethal effect on normal cells, which is a very valuable natural product. BA and its derivatives have shown great potential as biologics in anti-cancer and HIV treatment, and are of great value for the research and development of new drugs.

Xi'an Healthkintai^® is a leading manufacturer of high-quality betulinic acid. Using advanced extraction and purification technologies, we provide pharmaceutical-grade products with a purity consistently exceeding 98%. Our GMP-compliant production process ensures exceptional stability and reliability. This product exhibits significant anti-cancer activity (particularly against melanoma) and can specifically induce apoptosis in cancer cells. It also possesses multiple biological benefits, including antiviral, anti-inflammatory, and antibacterial properties. If you need high-quality betulinic acid, please feel free to contact us.

Kintai Betulinic Acid Advantages

• High Quality:Kintai utilizes cutting-edge chromatographic purification technology and a rigorous quality control system to ensure betulinic acid product purity exceeding 98% and excellent batch-to-batch stability, providing a solid foundation for high-end research and production.
• Customizability:We deeply understand the diverse needs of R&D and can flexibly accommodate orders ranging from grams to kilograms. We also support customized specifications in terms of purity, particle size, and solvent solubility to precisely match your specific experiments or applications.
• Multi-Application:Our high-purity betulinic acid is an ideal raw material for the development of new anti-cancer drugs, antiviral formulations, high-end functional skincare products, and natural antibacterial products. It can be used in a variety of fields, including pharmaceuticals, cosmetics, and health supplements.

1. Anticancer and Antitumor Activity​​​​​​​

Selective Cytotoxicity: It can specifically induce apoptosis in various cancer cells, but has low toxicity to normal cells, resulting in a high safety profile.

2. Antiviral Effects

Inhibits HIV replication and maturation, particularly significantly inhibiting HIV-1 protease activity. It also has inhibitory effects on hepatitis C virus (HCV), influenza virus, and herpes simplex virus (HSV).

3. Anti-inflammatory and Immunomodulatory Effects

Inhibits the production of inflammatory factors (such as TNF-α and IL-6), regulates inflammatory pathways such as NF-κB, and alleviates chronic inflammatory diseases (such as arthritis and enteritis).

4. Antibacterial and Antiparasitic Effects

It has inhibitory effects on various bacteria (such as Staphylococcus aureus) and fungi (such as Candida albicans), and also has antiparasitic effects against parasites such as Plasmodium.

5. Liver Protection and Lipid-Lowering Effects

It reduces liver damage, inhibits liver fibrosis, and lowers cholesterol and triglyceride levels by regulating lipid metabolism.

6. Skin Repair and Antioxidant Benefits

Promotes wound healing, inhibits skin inflammation (such as acne), and possesses strong antioxidant properties, reducing free radical damage.

1. Pharmaceutical Industry

This is the most valuable and promising application area for betulinic acid, primarily focused on innovative drug development. It is considered a promising new anti-cancer lead compound and has also shown potential against hepatitis C virus (HCV), influenza virus, and herpes simplex virus (HSV).

2. Cosmetics and Personal Care Industry

​​​​​​​Btulinic acid's anti-inflammatory, antioxidant, and antibacterial properties make it an ideal raw material for high-end cosmetics.

It is used in acne serums and lotions to effectively inhibit Propionibacterium acnes and reduce skin redness, swelling, and inflammation. Its powerful antioxidant capacity can neutralize free radicals and is used in anti-wrinkle serums and creams.

3. Health Products and Functional Food Industry

As a dietary supplement, its preventive and health-promoting properties are primarily promoted. It is being used in the development of health products to soothe alcohol consumption, protect the liver, and reduce chemical-induced liver damage. Based on its research on lipid-lowering and anti-atherosclerotic effects, it is being used to assist in regulating blood lipid and cholesterol levels. Its anti-inflammatory and antioxidant properties are being utilized as a supplement to enhance immunity and combat fatigue.

4. Agriculture and Veterinary Pharmaceuticals

Green pesticides: Utilizing their natural antibacterial and antifungal properties, we are developing botanical biopesticides to control crop diseases and reduce chemical pesticide residues. As feed additives, they aim to enhance livestock immunity, prevent disease, and promote growth, offering a potential alternative to antibiotics.

• Reliable Quality and Supply Assurance:The betulinic acid raw materials we provide are sourced from a clearly defined and controlled source and manufactured under strict GMP and HACCP quality management systems. Each batch of product comes with a detailed specification sheet and certificate of authenticity (COA). Our sophisticated production processes and ample production capacity ensure a stable and consistent supply of high-quality raw materials.
•  Excellent Product Performance and Ease of Use:Our powdered product exhibits excellent physical and chemical stability, making it easy to mix, granulate, compress, or fill in your production process. Compared to some iron sources, it is less likely to cause discoloration or off-flavor in the final product.
• Comprehensive Technical Value-Added Services:We provide application advice, formulation guidance, market information sharing, and in-production technical support (e.g., solubility, compatibility, and stability issues). Furthermore, we can explore customized solutions based on your specific requirements (e.g., particle size, carrier, and concentration).​​​​​​​