Chrysin Powder

Product Details

Xi'an Kintaihealth® leverages cutting-edge purification technology to deliver premium pharmaceutical-grade Chrysin Powder (CAS: 480-40-0) with consistent purity exceeding 98%. Our GMP-certified manufacturing processes ensure high bioactivity and stability, making this flavonoid ideal for nutraceuticals targeting antioxidant and immune support, anti-aging skincare formulations, and pharmaceutical research in neuroprotection and inflammation modulation. Committed to excellence, we provide customizable bulk supplies with stringent quality control—every batch undergoes rigorous HPLC/GC-MS testing to meet ISO, USP, and pharmacopoeia standards, guaranteeing ultra-low heavy metals (≤1ppm) and residual solvents (≤50ppm). As your trusted partner, we deliver reliable, high-performance Chrysin Powder to elevate product efficacy across cosmetics, supplements, and drug development.

 What is Chrysin Powder? 

Chrysin powder is mainly extracted from the Bignoniaceae plant Oroxylum indica, the Pinus chinensis and Pinus foetida plants of the Pinaceae family, and can also be obtained from traditional medicinal and edible raw materials such as Astragalus and propolis. Studies have shown that chrysin has a wide range of pharmacological activities, such as anti-tumor effects, anti-allergic effects, anti-inflammatory effects, anti-viral effects, anti-pathogenic microorganism effects, and hypoglycemic effects. If you have any ordering needs for chrysin, please contact us!

 Chrysin Powder Specifications 

HPLC chromatogram

 Chrysin Powder Extraction from Dicot Plants 

Kintai's Proprietary Bio-Enzymatic Process

1. Raw Material Preparation

· Plant Selection: Sourced from Oroxylum indicum seeds (Bignoniaceae family) and propolis-rich dicots, containing 0.8-1.2% chrysin by dry weight

· Pre-treatment:

o Low-temperature drying (40°C) to preserve flavonoid integrity

o Mechanical milling to 60-80 mesh particle size for optimal solvent penetration

2. Bioenzyme-Assisted Cell Disruption

Kintai's patented enzymatic hydrolysis enhances yield by 35-40% compared to conventional methods

· Enzyme Cocktail: Cellulase (50 U/g) + pectinase (30 U/g) in pH 5.0 buffer

· Process Parameters:

o Temperature: 50±2°C

o Duration: 3 hours with 40kHz ultrasound assistance

o Solid-liquid ratio: 1:4 (w/v)

3. Ethanol Gradient Extraction

· Primary Extraction: 85% ethanol at 80°C for 2 hours (repeated twice)

· Innovative Additives:

o 0.1% ascorbic acid to prevent oxidation

o Microwave assistance (800W pulsed mode) reduces extraction time by 30%

4. Multistage Purification

Chromatographic Sequence:

1. Macroporous Resin (D101) Adsorption:

o Dynamic adsorption capacity: 28 mg chrysin/g resin

o Elution with 70% ethanol at 1.5 BV/h flow rate

2. Silica Gel Chromatography:

o Mobile phase: Chloroform-methanol (8:2 v/v)

o Collect fractions with Rf 0.4-0.5 (TLC monitoring)

5. Crystallization & Drying

· Crystallization: Slow cooling (2°C/min) from 60°C to 4°C in 95% ethanol

· Final Processing:

o Vacuum drying at 50°C (<0.5% moisture)

o Particle size standardization to 100-150μm

Key Technological Advantages

1. Yield Optimization: Achieves 92-95% recovery of plant-source chrysin

2. Purity Control: HPLC-verified ≥98% purity (CAS 480-40-0 standard)

3. Sustainability:

o 90% ethanol recycling system

o Enzyme-based process reduces chemical waste by 60%

For full technical dossier including COA templates and OEM process customization, contact our R&D team at techsupport@kintai.com.

 Chrysin Powder Benefits 

Potent Antioxidant Activity
Neutralizes free radicals 3× more effectively than standard flavonoids (*ORAC: 25,000 μmol TE/g*), protecting cells from oxidative stress and slowing premature aging.

Anti-Inflammatory & Soothing Action
Inhibits COX-2 and TNF-α pathways, reducing redness and irritation without steroid-related side effects.

Anti-cancer

It can inhibit the activity of carcinogens in the human body, prevent cancer cell reproduction, reduce the incidence of cancer, and prevent cancer from spreading.
Anti-radiation: Chrysin has a strong anti-radiation ability, which can reduce the damage of radiotherapy and chemotherapy to the body.
Cardiovascular protection: It has anti-coagulation ability, can increase platelet activity, promote blood circulation, and prevent thrombosis.

Enzyme Modulation for Enhanced Bioactivity
Boosts bioavailability of other actives (e.g., curcumin, resveratrol) by inhibiting metabolic enzymes like CYP3A4.

Thermal & pH Stability
Maintains >95% efficacy under high-temperature processing (up to 160°C) and pH 3–9 environments.

 Chrysin Powder Benefits 

Medicine: Chrysin can be used to synthesize anti-cancer, lipid-lowering, cardiovascular and cerebrovascular disease prevention, antibacterial, anti-inflammatory and other drugs. As an estrogen blocker, it can inhibit the proliferation and invasion of human cancer cells.
Health products: Chrysin is widely used in health products due to its antioxidant and anti-inflammatory properties, which helps to enhance immunity and delay aging.
Cosmetics: Chrysin has the ability to absorb ultraviolet rays and scavenge oxygen free radicals. It can be used in hair care products to promote hair growth, condition the skin and relieve tension.

Why Clients Choose Us

Pain Point Focus: Solves formulation challenges (stability, bioavailability, safety).

Proof-Backed: Third-party data on ORAC, cytotoxicity, and enzyme kinetics included.

Supply Chain Assurance: Heavy metals ≤1ppm, residual solvents ≤50ppm, microbiologically sterile.

Customization: Water-dispersible versions for beverages, microencapsulated formats for delayed release.

Let me know if you’d like technical dossiers or formulation case studies for specific industries!info@kintaibio.com

 Chrysin  Recommended Dosage Guidelines 

Important Considerations

 Safety of Kintai Chrysin Powder 

At Kintai, we prioritize the safety and quality of our chrysin powder throughout the entire production process, from raw material sourcing to final packaging. Our commitment to safety is reflected in several key aspects:

Natural Raw Materials: We promise that our raw materials are naturally grown without any additives. This ensures that our chrysin powder is derived from pure, uncontaminated sources, minimizing the risk of contaminants or impurities.

Customized Extraction Solutions: Our advanced extraction techniques and customized solutions allow us to produce chrysin powder in various specifications tailored to your requirements. This not only meets your specific needs but also ensures that the extraction process is optimized for safety and efficiency.

Internationally Recognized Certifications: Our production facilities hold internationally recognized certifications, including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL. These certifications guarantee that our production processes adhere to the highest standards of quality, safety, and hygiene. They provide you with peace of mind, knowing that our chrysin powder is produced in a controlled and regulated environment.

Rigorous Testing and Quality Control: We implement rigorous testing and quality control measures at every stage of the production process. From raw material inspection to final product testing, we ensure that our chrysin powder meets or exceeds industry standards for purity, potency, and safety. Our quality control team uses advanced analytical methods, such as High-Performance Liquid Chromatography (HPLC), to accurately determine the chrysin content and confirm the absence of any contaminants.

Sustainable and Environmentally Friendly Practices: Kintai is committed to sustainability and environmentally friendly practices. We strive to minimize our environmental impact by using eco-friendly extraction methods, recycling solvents, and reducing waste. Our production processes are designed to be energy-efficient and to minimize carbon emissions.

In summary, the safety of Kintai chrysin powder is ensured through our commitment to natural raw materials, customized extraction solutions, internationally recognized certifications, rigorous testing and quality control, and sustainable practices. We take every step necessary to ensure that our chrysin powder is safe, pure, and of the highest quality, giving you the confidence to use it in your products and applications.

 OEM and ODM Services 

Kintaihealth^® is your trusted mate for OEM and ODM services. With a robust structure and a commitment to invention, we unite with guests to produce bespoke chrysin powder phrasings acclimatized to their specific conditions. Our intertwined service results insure a flawless experience from conception to product.

 Why Choose Chrysin Powder by Kintaihealth^®? 
1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce Chrysin powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.

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