Senna Leaf Extract Powder

Senna Leaf Extract Powder Manufacturer/Supplier

Senna leaf extract powder is obtained from the leaves of the Senna plant (Senna alexandrina Mill.), experimentally known as Senna alexandrina or Cassia Angustifolia. The principal bioactive compounds present in senna leaves are sennosides. Senna extract may help with constipation due to the laxative property. The really dynamic constituents in the powder are senna glycosides, especially sennosides A and B.

Healthkintai^® is a professional manufacturer of plant extract. Our top-selling specification is 20% sennosides (A+B) senna leaf extract powder, and if you need 6%, 8%, 10%, 30%, or 60% sennosides (A+B) specifications, we can also provide you with them. Please feel free to contact us at health@kintaibio.com.

The TDS of Senna Leaf Extract Powder

Regulatory Status of Senna Leaf Extract

United States (FDA)

Senna is an FDA-approved nonprescription (OTC) drug for adults and children ages 2 years and older. It should be taken at bedtime and tends to work within 6-12 hours. It might cause stomach upset and diarrhea. Senna should not be used for more than 1 week without the supervision of a healthcare provider.

How to Make Senna Leaf Extract?

The botanical source of senna leaf extract

Our senna leaf extract is derived from the dried leaves of Senna alexandrina Mill., a species listed in the pharmacopoeia. We select premium raw materials sourced from regions abundant in sunlight and heat resources, such as Yunnan and Xinjiang. The large temperature differences between day and night in these areas can significantly enhance the natural accumulation of sennosides A and B in the leaves.

Extraction flowchart of senna leaf extract

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Senna Leaf Extract Benefits

Relieves Acute Constipation (Core Efficacy)

The core active ingredients, sennosides A and B, in senna leaf extract are not absorbed in the small intestine. After entering the large intestine, they are metabolically converted into rhein anthrone by the intestinal flora. This metabolite can stimulate the nerves of the large intestinal mucosa to accelerate the rate of intestinal peristalsis and simultaneously inhibit the reabsorption of water and electrolytes by the intestinal mucosa, thereby increasing the water content in the intestinal tract and promoting defecation. It is suitable for the short-term relief of acute functional constipation.

Cleanses Intestinal Cleansing Before Surgery/Examination

Based on the potent yet controllable laxative effect of senna leaf extract, administration of a standardized dose can rapidly empty intestinal contents within 4–8 hours, reducing interference from intestinal residues with the surgical or endoscopic field of view. Its target of action is concentrated in the large intestine, with minimal impact on small intestinal absorption function and relatively controllable safety. Therefore, it is widely used for intestinal preparation prior to abdominal surgery and colonoscopy.

Mild Anti-inflammatory Effect and Intestinal Microecological Regulation

Anthraquinone derivatives such as rhein and aloe-emodin in senna leaf extract can inhibit the excessive proliferation of certain harmful intestinal flora and alleviate the inflammatory edema of the intestinal mucosa simultaneously. In addition, its function of promoting intestinal peristalsis shortens the retention time of feces in the intestinal tract, reduces the production and absorption of harmful substances, and indirectly helps maintain the balance of the intestinal microecology.

Senna Leaf Extract Applications

In the Pharmaceutical Field

Mainly available as OTC non-prescription drugs, including single-ingredient preparations such as senna leaf tablets, capsules, and granules, or compound preparations combined with dietary fiber and probiotics. The sennosides A+B content must comply with pharmacopoeial standards (8%–12%). 

In the Dietary Supplements Field

In the field of dietary supplements, senna leaf extract focuses on natural intestinal health management, with its core positioning being to support intestinal peristalsis and maintain regular bowel movements. Its common product forms include single-ingredient capsules and tablets with a sennosides A+B content of 8%–12%, or compound preparations formulated in combination with dietary fiber, probiotics and prebiotics.

Senna Leaf Extract Dosage and Side Effects

The dosage of senna leaf extract must be strictly controlled according to application scenarios.

In the pharmaceutical field, for the treatment of acute constipation or intestinal preparation, the single intake dose of sennosides A and B for adults shall not exceed 20 mg, and the daily dose shall not exceed 34.8 mg.​​​​​​​

In the field of dietary supplements, the recommended daily intake of sennosides A and B for adults shall not exceed 30 mg. Continuous use in both scenarios should not last more than 7 days, and children, pregnant women, and patients with hepatic or renal insufficiency should use it with caution or follow the doctor’s advice.

Common side effects are mostly gastrointestinal reactions such as abdominal pain, bloating, and diarrhea, which usually occur in cases of overdose or in sensitive populations.

Where to Buy Senna Leaf Extract Powder?

• With over a decade of dedicated commitment to the R&D of plant extracts, Healthkintai^® is fully capable of meeting all your requirements for product specifications. We mainly offer the 20% sennosides(A+B) senna leaf extract powder, while we can also customize other specifications for you. If you want to order, contact us at health@kintaibio.com.

  

• We are pleased to provide comprehensive OEM & ODM services tailored to your specific requirements.

  

• We boast complete qualifications and a full range of certifications. Our company has obtained the certifications of ISO 9001 Quality Management System, GMP (Good Manufacturing Practice), and HACCP Food Safety Management System.

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FAQ

1. Does senna make you lose weight?

Stimulant laxatives (including Boots Senna 7.5mg Tablets Adult) do not help with weight loss. They do not reduce the absorption of calories or nutrients. They can cause watery stools (diarrhoea), abdominal cramps and dehydration. Dehydration can seem like weight loss.

2. Why take senna at night?

Senna comes as a liquid, powder, granules, chewable pieces, and tablets to take by mouth. It is may be taken once or twice daily. Senna normally causes a bowel movement within 6 to 12 hours, so it may be taken at bedtime to produce a bowel movement the next day.