Aloe Emodin Powder

Aloe Emodin can be extracted from aloe vera and rhubarb, is a kind of orange acicular crystal (toluene) or soil yellow crystalline powder of chemical substances, has many benefits to human health, can inhibit cholesterol absorption, effectively promote intestinal peristalsis, with anti-tumor activity, antibacterial activity and immunosuppressive effect, is widely used as drugs, cosmetics raw materials.

KINTAI stands as a distinguished and reliable 95%Aloe Emodin Powder manufacturer and supplier, committed to providing premium quality products for professional buyers and global dealers. Our comprehensive range of aloe emodin is backed by a state-of-the-art Research and Development (R&D) center, advanced production base, and cutting-edge equipment. KINTAI boasts multiple patents, certificates, and Quality System Certifications, ensuring the highest standards in product quality.If you want to buy Aloe Emodin,please feel free to contact us at health@kintaibio.com.

Aloe-emodin has significant anti-tumor potential, demonstrating promising anti-cancer effects against a variety of malignancies, including lung, liver, breast, colorectal, and nasopharyngeal cancers. Compared to commonly used chemotherapy and radiotherapy, single components of traditional Chinese medicine are safer and more convenient in current cancer treatments, offering far-reaching implications and significant potential.

Telomerase plays an important role in the proliferation of tumor cells. In three different types of breast cancer cells, MDA-MB-453, MDA-MB-231, and MCF-7, aloe-emodin can upregulate the expression of transcription factor E2F1 and downregulate the expression of c-myc protein, thereby reducing the transcription of the telomerase reverse transcriptase (hTERT) gene, leading to telomere shortening, thereby inhibiting the proliferation of breast cancer cells.

Malignant tumors are harmful to human health, and aloe-emodin can exert anti-tumor activity in multiple ways. Compared with Western medicine, its advantages lie in promoting tumor cell apoptosis and inhibiting proliferation. It also shows good therapeutic effects in anti-inflammatory, antiviral, and immune regulation.

(Reference: Research progress on anti-tumor mechanism of aloe-emodin,CHEN Shan-lin1 , LIU Chuan-yu 2 , XIAO Sheng-jun 1, TANG Jian-hong11. The Second Affiliated Hospital of Guilin Medical University, Guilin 541199, China2. Affiliated Hospital of Guilin Medical University, Guilin 541001, China)

1.Anti-tumor effect

In recent years, the potential effect of aloe emodin in the field of anti-tumor has attracted extensive attention in scientific research circles at home and abroad. Its remarkable anti-cancer properties have covered a variety of tumor types, including but not limited to neuroectodermal tumors, liver cancer, lung squamous cell carcinoma, skin Merkel cell carcinoma, gastric cancer, and leukemia, showing a broad anti-cancer spectrum. In particular, Aloe Emodin Powder showed significant inhibition in experiments targeting P388 leukemia cells, helping to prolong the survival of patients. This effect is partly attributed to its ability to interfere with and inhibit the biosynthesis of DNA, RNA and proteins in cancer cells, thereby hindering the proliferation and spread of cancer cells, providing new strategies and ideas for tumor treatment.

2.Antibacterial action

Aloe emodin exhibits strong antibacterial activity, showing remarkable effects against a range of bacteria, especially staphylococcus and streptococcus, which are highly sensitive to it. In addition, it can also effectively fight diphtheria, subtilis, anthrax, paratyphoid and dysentery and other bacteria. One of its antibacterial mechanisms is to inhibit the physiological function of bacteria by blocking the electron transfer process of mitochondrial respiratory chain. It is particularly worth mentioning that aloe emodin has a strong inhibitory effect on nucleic acid and protein synthesis of Staphylococcus aureus, which provides a new therapeutic approach for the treatment of infections caused by these bacteria.

3.Reduce fat and lose weight

 Aloe emodin shows the potential of lipid reduction and weight loss in health management. It helps to regulate the balance of lipids in the body by inhibiting the absorption of cholesterol and promoting the smooth peristalsis of the intestine, so as to play a certain role in lipid reduction and weight loss.

4.Purgative action

Aloe emodin has a strong purging effect, can stimulate intestinal wall peristalsis, promote the elimination of intestinal waste, constipation and hemorrhoids has a special effect.

Immunosuppressive action: Aloe emodin has the ability to regulate the immune system, it can inhibit the excessive production of antibodies in the biological body, and then alleviate the immune overreaction (that is, anti-allergic effect), while reducing the burden of immune organs, reflected in reducing the number of white blood cells and weakening the function of abdominal macrophages, helping to maintain the balance of the immune system.

1. Medical Field

• Laxative and Constipation Treatment: These are the most classic and widely known uses of aloe-emodin. It is metabolized by bacteria in the intestines into rhein anthrone, which stimulates colonic motility and inhibits water absorption, resulting in a mild laxative effect.
• Antibacterial and Antiviral: It has strong inhibitory effects against Gram-positive bacteria (such as Staphylococcus aureus and Streptococcus), and also has some effects against some Gram-negative bacteria and fungi. Its mechanism is to interfere with bacterial cell wall synthesis and protein metabolism. It has some inhibitory effects against herpes viruses, influenza viruses, and even human immunodeficiency virus (HIV), primarily by interfering with the viral replication cycle.
• Anti-tumor: This is currently the most actively researched area. Aloe-emodin has been shown to inhibit proliferation and induce apoptosis (programmed cell death) and autophagy in various cancer cells (such as liver cancer, gastric cancer, lung cancer, breast cancer, and leukemia).
• Anti-inflammatory and immunomodulatory properties: Aloe Emodin Powder can inhibit the production and release of inflammatory factors (such as TNF-α, IL-1β, and IL-6), alleviating inflammatory responses. It has potential therapeutic value for inflammatory diseases such as colitis and dermatitis.

2. Cosmetics and Personal Care Products
Aloe-emodin is a key ingredient in many 'aloe vera'cosmetics.

• Sunscreen and UV Protection: Aloe-emodin effectively absorbs UV rays (especially UVA and UVB), making it a common adjunct ingredient in natural sunscreens.
• Whitening and Spot-Reducing: By inhibiting tyrosinase (a key enzyme in melanin synthesis), it reduces melanin production, achieving whitening, brightening, and lightening effects.
• Anti-acne: Combined with its antibacterial (particularly inhibiting Propionibacterium acnes) and anti-inflammatory properties, aloe-emodin is widely used in cleansers and skincare products for acne treatment and oil control.
• Antioxidant and Anti-Aging Applications: Its powerful antioxidant capacity can neutralize free radicals and slow the degradation of collagen and elastin in the skin, thereby helping to delay skin aging and reduce wrinkles.

3. Health Products and Functional Foods

• Laxative Health Products: As a natural laxative, it is added to some health products to improve intestinal health and treat constipation.
• Immune Enhancement: Due to its immunomodulatory effects, it is also used in some health product formulas designed to boost the body's immune system.

4. Agriculture and Animal Husbandry

• Plant Growth Regulator: Low concentrations of aloe-emodin can promote seed germination and seedling growth in certain plants.
• Natural Pesticide: It has inhibitory and anti-bacterial effects on a variety of plant pathogens and pests, and has development potential as a botanical pesticide or fungicide, aligning with the development trend of green agriculture.
• Feed Additive: In the livestock industry, as a natural antibacterial and anti-inflammatory additive, it may be used to replace some antibiotics to prevent intestinal diseases and promote growth in animals. However, related research and applications are still in the exploratory stage.

1. Purely Natural Extraction: We rigorously select high-quality aloe vera as our raw material, ensuring not only the naturally intact molecular structure and high biological activity of Aloe Emodin Powder, but also the safety and purity of our product, fundamentally fulfilling your highest expectations for "natural origin."

2. High Quality: Every batch of Kintai's products undergoes rigorous testing to ensure the active ingredients are highly active and consistently high quality from batch to batch, providing reliable and efficient raw materials for your research and applications.

3. Flexible and Customizable: Whether you require a specific pharmaceutical-grade dosage form, the fineness and solubility required for cosmetics, or the specific formulation ratios required for health supplements, Kintai offers flexible customization services, from purity and dosage form to packaging, to fully meet your individual project needs.