Centella Asiatica Extract Asiaticoside Powder

Centella Asiatica Extract Asiaticoside Manufacturer and Supplier

Centella Asiatica Extract Asiaticoside Powder is a natural plant extract derived from the Centella asiatica plant. The extract contains a variety of active ingredients, mainly including triterpenoids, flavonoids, and other bioactive substances (such as ursolic acid, β-sitosterol, vitamin C, etc.). These components give the extract rich pharmacological effects.

KINTAI mainly manufactures: 80% Total asiatica glycosides; 95% Asiaticoside; 95% Madecassoside(Other specifications can be customized ).KINTAI is a professional manufacturer and supplier of Centella Asiatica Extract Powder. We have a dedicated research and development center, production base, and state-of-the-art equipment to ensure the highest quality products. Our integrated service solutions include customized product development, fast delivery, and secure packaging. For inquiries or to place an order, please contact us at info@kintaibio.com.

KINTAI Centella Asiatica Extract Specifications

Physicochemical Properties of Centella Asiatica Extract

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Benefits of Centella Asiatica Extract

Asiaticoside Wound Healing and Scar Repair Effects

 This is the most classic and well-documented efficacy of Guto Kola Extract. It significantly stimulates fibroblast proliferation and promotes the synthesis and orderly arrangement of collagen (especially type I and III) and extracellular matrix (such as fibronectin). Simultaneously, it reduces excessive scar formation by inhibiting inflammatory responses and regulating the transforming growth factor-β signaling pathway. Therefore, asiaticoside is widely used for the healing of surgical incisions, burns, and traumatic wounds, as well as for improving and preventing hypertrophic scars and keloids.

Anti-inflammatory and Antioxidant Activity

Asiaticoside effectively inhibits the production of various pro-inflammatory mediators, such as tumor necrosis factor-α, interleukin-1β, and prostaglandin E2, and reduces the activity of key inflammatory pathways (such as NF-κB and MAPK). Simultaneously, it enhances the activity of endogenous antioxidant enzymes such as superoxide dismutase, directly scavenging free radicals and reducing oxidative stress damage to cells. This lays the theoretical foundation for its application in treating inflammatory skin diseases and providing photoprotection.

Neuroprotective and Cognitive Improvement Potential

Recent studies have revealed that asiaticoside can penetrate the blood-brain barrier and have a positive impact on the central nervous system. It can protect neurons from damage through multiple pathways, including antioxidant, anti-inflammatory, and apoptosis-inhibiting effects. In cognitive impairment models such as Alzheimer's disease, asiaticoside has been shown to reduce β-amyloid deposition and Tau protein hyperphosphorylation, improve synaptic plasticity and memory function, demonstrating its potential as an adjunct therapy for neurodegenerative diseases.

Centella Asiatica Extract in Skincare

In the skincare field, asiaticoside repairs damaged skin barriers and enhances moisturizing capabilities by promoting the proliferation of epidermal keratinocytes and accelerating the synthesis of barrier-related proteins (such as filaggrin). Its antioxidant properties help combat photoaging caused by environmental factors such as ultraviolet radiation. Furthermore, it can stimulate collagen regeneration and inhibit the degradation of collagen by matrix metalloproteinases, thereby improving skin elasticity, reducing wrinkles, and achieving comprehensive anti-aging effects.

Uses of Centella Asiatica Extract

Centella Asiatica Extract Pharmaceuticals and Supplements

In the pharmaceuticals and medical devices field, asiaticoside is primarily used as an active therapeutic ingredient. Its core value lies in promoting tissue repair and regulating scar formation. In specific applications, it is formulated into creams, gels, sprays, or medicated dressings for direct application to various acute and chronic wounds, such as surgical incisions, burns, trauma, and slow-healing diabetic foot ulcers.

In scar management, Guto Kola Extract (often used in combination with asiatic acid) is both a wound treatment ingredient listed in the pharmacopoeias of many countries and a key active ingredient in scar repair medical devices (often as a supplement or alternative to silicone products). Furthermore, its anti-inflammatory properties are also used as an adjunct treatment for inflammatory skin diseases such as atopic dermatitis.​​​​​​​

Centella Asiatica Skincare Products

In the skin care and cosmetics field, asiaticoside is widely added to various product forms, including serums, lotions, creams, masks, and ampoules, primarily targeting common modern skin problems: sensitive skin, damaged skin barrier, and photoaging. For sensitive skin and skin with a damaged barrier (such as those caused by over-cleansing, cosmetic procedures, or environmental irritants), asiaticoside helps rebuild a healthy physical skin barrier; it also quickly soothes redness and burning sensations caused by external stimuli, providing an immediate calming effect.

In terms of anti-aging, it can slow down wrinkle formation and improve skin firmness and elasticity. Its repairing properties also make it a gold standard ingredient in post-cosmetic procedures (such as laser and microneedling) care products, effectively reducing post-operative inflammation and accelerating skin recovery.

Centella Asiatica Extract for Hair​

Centella Asiatica extract is widely used as a multi-functional repairing ingredient in daily personal care. In oral care, it is added to toothpaste or mouthwash to help reduce gum inflammation and promote oral mucosal repair. Furthermore, in hair care, asiaticoside is being studied for its potential to prevent hair loss and promote healthy hair follicles, providing anti-inflammatory and nourishing support to the scalp. It has expanded from a single skin repair ingredient into a comprehensive active ingredient covering multiple areas of the body.

Centella Asiatica Extract Side Effects

As a natural active ingredient, Guto Kola Extract generally has a high safety profile, but side effects may still occur in certain situations. When used topically (such as in skincare products or ointments), the most common side effect is mild skin irritation, manifesting as temporary redness, itching, or burning sensation at the application site, which is more common in individuals with extremely sensitive skin or severely compromised skin barriers. In rare cases, it may trigger contact dermatitis.There is currently insufficient clinical data to confirm asiaticoside absolute safety during pregnancy; it is recommended to consult a doctor.

Where to buy Best Centella Asiatica Extract​?

KINTAI, as a professional Centella Asiatica leaf Extract manufacturer and supplier, offers OEM and ODM services. We have a dedicated research and development center, production base to ensure the highest quality products. We also hold multiple patents and certifications for our quality management system.Feel free to contact us at info@kintaibio.com.
FAQ

Q1:Is Centella like retinol?

A1:Not at all. Centella and retinol work in fundamentally different ways. Retinol is a vitamin A derivative that primarily accelerates skin cell renewal and boosts collagen to combat wrinkles and photoaging, often causing initial irritation. In contrast, Centella (key compounds: madecassoside, asiaticoside) is a soothing, anti-inflammatory herb that focuses on calming redness, repairing the skin barrier, and aiding wound healing. It is ideal for sensitive skin and is frequently used to help soothe the irritation that retinol can cause.

Q2:Is Centella better than Niacinamide?

A2:Not "better," but different. They are complementary ingredients for distinct goals. Niacinamide excels at regulating oil, improving uneven skin tone, and strengthening the barrier. Centella (especially madecassoside/asiaticoside) specializes in intensive soothing, reducing redness, and repairing compromised or sensitive skin. For strong anti-inflammatory and wound-healing effects, Centella is superior. For overall barrier health and brightening, Niacinamide is more versatile. Often, they work best together in a balanced routine.

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