Gentiopicroside Powder

Gentiopicroside powder, as Healthintai^®'s star product, is derived from the natural plant gentian and is made through a precise extraction process. It is widely used in the fields of enhancing immunity, improving liver function and anti-oxidation, providing natural and efficient health solutions for the health care products, pharmaceuticals and cosmetics industries, and the market demand covers a wide range of markets around the world.

Our factory uses advanced technology to ensure that the purity of gentiopicroside is as high as 98%, and it has passed international standard tests such as HPLC, with excellent quality. The product appearance is fine powder, which is easy to process and apply.Choose Kintai and let us empower your brand value and market competitiveness with our high-quality raw materials and professional support.

KINTAI's Gentiopicroside Powder Advantages  

• High purity and standardization: The advanced extraction process ensures that the purity of  Gentian root extract powder, which meets the international GMP and ISO standards, and provides excellent quality assurance for your products.
• Natural source, safe and effective: Select high-quality p​​​​​​​lant raw materials, no chemical additives throughout the process, to ensure that the product is natural, pure, safe and effective, in line with the global market demand for green and healthy products.
• Significant biological activity: After strict quality control and scientific verification,  Gentian root extract powder shows excellent antioxidant, anti-inflammatory and other biological activities, adding unique selling points to your products.
• Flexible customization to meet needs: Provide a full range of customized services from raw material selection to product specifications and packaging to ensure that your products are unique and meet specific market needs.

Interested?We'd love to send you a free symple!    CONTACT US>>>

Plant Source

Kintai's gentiopicroside is sourced from high-quality gentian roots grown in the Heilongjiang, Jilin, and Liaoning mountainous areas of Northeast China, where the climate is cool, characterized by large diurnal temperature swings, ample sunlight, and excellent drainage, as well as in the Yunnan, Guizhou, and Sichuan plateaus of Southwest China. This unique climate and ecological environment are key factors in the production of high-quality gentian and its high gentiopicroside content. We maintain stringent quality control from planting to harvesting, striving to provide you with the highest standards and quality gentiopicrosides.​​​​​​​

Production Process

1. Extraction & Preliminary Purification
Dried gentian root is powdered and extracted with butanediol solution under ultrasonic heating. The filtrate is cooled, treated with activated carbon for decolorization and deodorization, and then filtered to obtain the crude extract.

2. Solvent Exchange & Column Adsorption
Butanediol is removed from the extract via reduced-pressure distillation, and ethanol is added to form the injection solution. This solution is adsorbed onto a column packed with catechin-modified macroporous resin.

3. Elution & Product Isolation
Gentiopicroside is eluted using an ethanol-water solution. The target fraction is collected, concentrated, and dried to yield pure gentiopicroside.​​​​​​​

Gentiopicroside has significant protective and conditioning effects on the hepatobiliary system, which is its core pharmacological activity. It can directly stimulate hepatocytes to secrete bile, promote gallbladder contraction, and dilate the bile duct, effectively promoting bile secretion and relieving jaundice. It is suitable for cholestasis and related jaundice. Gentiopicroside can also alleviate chemical or immune liver damage through antioxidant activities and inhibition of inflammatory factor release, protecting the integrity of liver cell membranes and improving liver function indicators. It also has a certain auxiliary therapeutic effect in acute and chronic hepatitis and alcoholic liver damage, demonstrating its excellent dual efficacy of liver protection and bile promotion.​​​​​​​

(Gentiopicroside improves DSS-induced ulcerative colitis and secondary liver injury in mice by enhancing the intestinal barrier and regulating the gut microbiome)

1. Hepatoprotective and Choleretic Effects

Gentiopicroside significantly stimulates bile secretion from hepatocytes, promotes gallbladder contraction and biliary tract dredging, effectively alleviating cholestasis and providing adjuvant therapy for icteric hepatitis and cholecystitis. Furthermore, through antioxidant and anti-inflammatory mechanisms, it inhibits hepatocellular damage, mitigates liver damage caused by chemicals or alcohol, and restores liver function, demonstrating the dual efficacy of "soothing the liver and promoting bile."

2. Anti-inflammatory and Analgesic Effects

Gentiopicroside inhibits key inflammatory signaling pathways such as NF-κB, reducing the release of inflammatory factors such as TNF-α and IL-6. It exhibits excellent anti-inflammatory effects in inflammatory models such as gastritis, enteritis, and arthritis. Its analgesic effects are related to regulating peripheral and central pain perception and can be used to alleviate chronic inflammatory pain.

3. Antibacterial and Antiviral Effects

Studies have shown that gentiopicroside has inhibitory effects against a variety of Gram-positive and Gram-negative bacteria, such as Staphylococcus aureus and Escherichia coli. Regarding viruses, it can interfere with the viral replication cycle and has the potential to inhibit some respiratory viruses and hepatitis viruses, making it a natural antibacterial and antiviral adjuvant.

4. Promoting Digestion

Gentiopicroside can inhibit excessive gastric acid secretion, reduce gastric mucosal damage, and promote the proper secretion of digestive juices, demonstrating a significant protective effect against experimental gastric ulcers. It can also regulate intestinal motility, relieve spasmodic abdominal pain, and improve functional dyspepsia.

​​​​​​​​​​​

 1. Pharmaceuticals

Gentian root extract powder is a core ingredient in liver-protecting and choleretic traditional Chinese medicine preparations, widely used in clinical adjuvant treatments for acute and chronic hepatitis, cholecystitis, and jaundice. Its anti-inflammatory and analgesic properties are also used to alleviate the symptoms of arthritis and gastroenteritis. Recent studies have revealed its antidepressant and neuroprotective potential, providing new avenues for the development of therapeutics for neurological diseases.

2. Functional Foods and Health Products

Gentiopicroside, due to its liver-protecting and hangover-relieving properties, has been developed as a hangover-relieving and liver-protecting health product. It can alleviate alcoholic liver damage by enhancing the activity of liver ethanol metabolizing enzymes. Its digestive and anti-ulcer properties have also led to its use in the development of health foods for gastrointestinal function conditioning.

3. Cosmetics

Gentiopicroside's antibacterial and anti-inflammatory properties are used in acne-removing and soothing skincare products, effectively inhibiting Propionibacterium acnes and reducing skin inflammation. Its antioxidant capacity can also help delay photoaging, making it a new choice as a natural functional cosmetic ingredient.

4. Animal Husbandry

As a natural plant extract, gentiopicroside is used as a feed additive to replace some antibiotics. Studies have shown that it can improve intestinal health in livestock and poultry, reduce diarrhea rates, and enhance animal immunity, meeting the needs of sustainable animal husbandry.​​​​​​​

5. Research and Biotechnology

Due to its unique iridoid structure and diverse biological activities, gentiopicroside is often used as a reference and lead compound in natural product chemistry research. In biotechnology, researchers are attempting to increase its production through cell culture and biosynthesis techniques, providing new solutions to address resource shortages.​​​​​​​

• ​​​​​​​​​​​​​​​​​​​​Improve product competitiveness: High-quality, standardized Gentiopicroside add unique benefits to your products and enhance market competitiveness.
• Shorten the R&D cycle: We provide detailed product info and technical support to help you quickly complete product development,seize market opportunities.
• Stable supply chain: With a stable supply of raw materials and production capacity, we ensure stable supply and reasonable prices in long-term cooperation.​​​​​​​​​​​​​​

As a leading Gentiopicroside supplier, Kintai ensures GMP-certified production and global compliance for reliable bulk sourcing.Among top Gentiopicroside manufacturers, Kintai stands out for its strict quality control and batch-to-batch consistency.Kintai operates a state-of-the-art Gentiopicroside powder factory with ISO, HALAL, and KOSHER certifications for global distribution.

Q: How fast is the delivery of your product?

A: We prioritize fast delivery, ensuring your products reach you instantly without compromising quality.

Q: Are you a certified manufacturer?

A: Yes, Kintai is a professional Gentiopicroside manufacturer and supplier. We have a dedicated research and development center, production base, and advanced equipment. We have different licenses and affirmations to guarantee the best norms are met.

Assuming that you are searching for Gentiopicroside, please contact us at info@kintaibio.com. We are your believed accomplice in accomplishing your well-being and health objectives.